Publications by authors named "Cunze Wang"
Article Synopsis
- Renal cell carcinoma (RCC) is a prevalent and deadly form of cancer, with a significant portion of cases being the metastatic variant (mRCC), making treatment challenging; temsirolimus (TEM) is an approved therapy for advanced cases but has limitations due to poor water solubility and side effects.
- This study focused on creating a new drug delivery system using a block copolymer (mPEG-PBAE) to enhance the effectiveness of TEM through pH-responsive nanoparticles that release the drug in specific conditions.
- Results showed that the new micelles significantly improved TEM's water solubility, allowing for effective drug loading, a rapid release in acidic environments, and promising drug delivery properties without major toxicity issues.
The causal effects of mental health problems on the risk of infectious diseases remain vague. Investigating them via observational study is challenging as it presents possible confounding factors. Therefore, the objective of this study was to utilize Mendelian randomization (MR) techniques to evaluate the causal relationship between mental health problems and the risk of infectious diseases.
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