Publications by authors named "Cunneng Li"
Herein, we present that treating -(2-oxo-2-phenylethyl) substituted 2-pyridones with styrenes in DMSO/HO at 120 °C affords 1,6-carboannulated 2-pyridone scaffolds with up to 79% yield. This protocol provides a simple and efficient method for obtaining complicated bicyclic 2-pyridones through a radical cascade reaction. Additionally, we have successfully synthesized 27 target compounds, which confirms the practicality and wide applicability of the proposed reaction.
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- - Alzheimer’s disease is a serious condition characterized by neurodegeneration, with factors like neuroinflammation and β-amyloid buildup playing key roles in its development.
- - Erjing Pills have the potential to reduce neuroinflammation through the inhibition of a specific inflammatory pathway, but more research on their active components is needed.
- - This study used various methods to identify 59 drug ingredients in Erjing Pills, highlighted diosgenin's strong binding abilities and its involvement in processes that may reduce inflammation and improve cognitive function, suggesting its potential for Alzheimer's treatment.