Publications by authors named "Cunli Nong"

Article Synopsis
  • - The study investigates the link between genetic variants in the p53 signaling pathway and survival rates in patients with hepatitis B virus-related hepatocellular carcinoma (HBV-HCC), focusing on 4698 single nucleotide polymorphisms (SNPs) across 70 genes.
  • - Researchers discovered two specific SNPs, rs7925603 A > G and rs4396625 A > T, which significantly affect overall survival outcomes for HBV-HCC patients, suggesting that these variants may alter mRNA expression levels.
  • - The findings highlight the need for larger studies to further validate the role of these SNPs in influencing survival in HBV-HCC, as they may provide insights into cancer prognosis and treatment strategies.
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Background: Super-enhancer (SE) refers to a regulatory element with super transcriptional activity, which can enrich transcription factors and drive gene expression. SE-related genes play an important role in the pathogenesis of malignant tumors, including hepatocellular carcinoma (HCC).

Methods: The SE-related genes were obtained from the human super-enhancer database (SEdb).

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Scrub typhus is often misdiagnosed in febrile patients, leading to antibiotic abuse and multiple complications. We conducted a retrospective record review at the Fourth Affiliated Hospital of Guangxi Medical University in China. Data were collected on 52 patients with a confirmed diagnosis of scrub typhus and complete clinical data.

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miRNAs play an indispensable role in human carcinogenesis. Dysregulated miR-1180-3p has been observed in several types of cancer, including hepatocellular carcinoma (HCC). This study intends to correlate the expression level of miR-1180-3p with clinical features and overall survival in HCC patients.

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