Publications by authors named "Cun-Zu Wang"
Objective In cerebral aneurysm clipping and embolization, blood pressure control and temporary parent artery blocking are common methods to prevent aneurysm rupture. Their influence on the prognosis is uncertain. In this study, we try to find out the association between methods above and prognostic indicators.
View Article and Find Full Text PDFLiver transplantation is associated with a significantly increased risk of de novo malignancies, but for renal cancer this risk is less clear. We therefore performed a meta-analysis of published studies to determine whether renal cancer risk in liver transplant recipients (LTRs) was increased. To obtain a more precise conclusion, a systematic search was performed in PubMed and Web of Science databases until June 10, 2015.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to analyze how gradient decompression techniques impact intraoperative hypotension and patient outcomes in traumatic brain injury cases over a four-year period.
- It evaluated data from 186 patients, examining factors like pupil abnormalities, Glasgow Coma Scale scores, and various decompression methods (mannitol, hyperventilation, and graded craniotomy) while measuring their association with hypotension and prognosis.
- The results revealed that gradient decompression methods had no significant effect on intraoperative hypotension or patient prognosis, highlighting the need for alternative clinical approaches for treating severe traumatic brain injury.
[The construction of lentivirus-mediated RNAi vector containing hTERT].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
February 2008
Objective: To construct a recombinant lentivirus RNA interference (RNAi) vector carrying hTERT gene, and to obtain the titer of the lentiviral stock for investigating the expression in the eukaryotic cells and the effect on the hTERT gene silencing in the eukaryotic cells.
Methods: Two complimentary oligos of small interference RNA (siRNA) with hairpin structures targeting the hTERT gene and a negative control were synthesized, then ligated with pLVTHM vector and sequenced. The recombinant vectors were then transfected with viral packaging mix into T293 cells, viral supernatant was harvested to determine the titer.
[Study on combined gene therapy for malignant gliomas transfected with antisense hTERT/PTEN in vitro and in vivo].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
December 2006
Objective: To study inhibitory efficacy of combined gene therapy for malignant gliomas transfected with antisense human telomerase reverse transcriptase (hTERT)/PTEN in vitro and in vivo.
Methods: To construct two adenovirus recons which contained antisense hTERT and wild-type PTEN respectively with high performance homologous recombination system in bacteria. The two adenovirus recons were transfected into U251 human malignant glioma cells combinedly or respectively in vitro and in vivo.