Publications by authors named "Cun-Ying Cui"
The prognosis of right heart enlargement varies according to different etiologies. The purpose of this study was to investigate the characteristics of echocardiogram, surgical treatment, chromosome and prognosis for fetal right heart enlargement.The foetal echocardiogram was performed on 3987 pregnant women, and then 88 fetuses with right heart enlargement were identified.
View Article and Find Full Text PDFThe aim of this study was to explore the effects of nonvalvular atrial fibrillation (NVAF) on the structure and function of mitral valve and analyze independent risk factors of moderate to severe mitral regurgitation (MR) by quantitative measurement of mitral parameters using real-time 3-dimensional transesophageal echocardiography.This study included 30 subjects with sinus rhythm group, and 65 patients with NVAF. The 65 patients with NVAF were divided into 35 with paroxysmal atrial fibrillation group and 30 with persistent atrial fibrillation.
View Article and Find Full Text PDFObjective: The objective of this study was to evaluate the feasibility of online real time three-dimensional transesophageal echocardiography (RT3DTEE) in the measurement of left atrial appendage (LAA) orifice size. We also analyzed the correlation between LAA ejection fraction (EF) and its peak empty velocity (PEV).
Methods: There were 91 subjects enrolled in this study, with 46 patients with AF and 45 individuals with sinus rhythm (SR).
Article Synopsis
- Tetralogy of Fallot is a common congenital heart condition, but its genetic causes are not well understood, prompting this study to investigate genetic variants using whole exome sequencing.
- The researchers analyzed DNA from eight small families to find specific genetic differences, discovering sixteen single nucleotide polymorphisms (SNPs) and eight small insertions/deletions (InDels) linked to the condition.
- Their findings highlighted several novel genetic mutations that could be responsible for isolated Tetralogy of Fallot, enhancing the understanding of its pathology.
Background: Little information is available regarding the penetrance of 1q21.1 copy number variants (CNVs). In the present study, we explored the clinical significance of 1q21.
View Article and Find Full Text PDFApplication of array-comparative genomic hybridization in tetralogy of Fallot.
Medicine (Baltimore)
December 2016
Article Synopsis
- A study analyzed chromosome karyotypes and genome-wide copy number variations (CNVs) in 86 patients with tetralogy of Fallot (TOF) to understand its pathogenesis and aid genetic counseling and prenatal diagnosis.
- All patients had normal karyotypes, but CNVs were found in 11 individuals, including deletions and duplications in specific chromosome regions.
- The use of array-comparative genomic hybridization (aCGH) proved effective in detecting CNVs, offering insights into congenital heart disease and validating the importance of genetic testing for TOF.
Analysis of etiology, chromosome and prognosis for small left heart system development in 69 fetuses.
J Matern Fetal Neonatal Med
October 2016
Objective: To provide a basis for evaluating the prognosis of small left heart system development in fetuses, we analyzed its related factors.
Methods: The fetal echocardiogram was performed in 3859 pregnant women, and then small left heart system development was identified in 69 fetuses. The data of prenatal and postnatal echocardiograms, postnatal cardiac surgical treatment, chromosome and autopsy after induced labor were analyzed in the 69 fetuses.