Single-dose pharmacokinetics and safety of iptakalim hydrochloride in Chinese healthy volunteers.

Objectives: To investigate the safety, pharmacokinetics and food effect of iptakalim in healthy adult Han Chinese volunteers.

Methods: Study 1 was a randomized open-label, Latin square designed, single-dose, three-period, self-control crossover study. Six men and six women received 5, 10 and 20 mg of iptakalim orally.