MEMS infrared light source stress optimization and reliable package design.

Aiming at the effects caused by stress and deformation on Micro-Electro-Mechanical System (MEMS) sensors, the stress distribution in the radiation area of the MEMS infrared light source is investigated, and by simulating and optimizing the thickness of the composite support film of the chip structure in COMSOL, a film layer thickness matching with lower stress and deformation for the MEMS infrared light source is derived. The utilization of the particle swarm algorithm and backpropagation neural network model allowed for the optimization of simulation data, enabling regression prediction over a broader range of thicknesses and providing a more precise depiction of the stress distribution trend. In addition, the specifications of the MEMS device help us to analyze the design of the support film thickness in the processing of the residual stress within the controllable range.

Potential contribution of early endothelial progenitor cell (eEPC)-to-macrophage switching in the development of pulmonary plexogenic lesion.

Background: Plexiform lesions, which have a dynamic appearance in structure and cellular composition, are the histological hallmark of severe pulmonary arterial hypertension in humans. The pathogenesis of the lesion development remains largely unknown, although it may be related to local inflammation and dysfunction in early progenitor endothelial cells (eEPCs). We tested the hypothesis that eEPCs contribute to the development of plexiform lesions by differentiating into macrophages in the setting of chronic inflammation.

Clinical significance of serum lipids in idiopathic pulmonary alveolar proteinosis.

Background: It is well known that pulmonary alveolar proteinosis(PAP) is characterised by accumulation of surfactant lipids and proteins within airspaces. However, few previous data describe the serum lipid levels associated with PAP.

Materials And Methods: We retrospectively reviewed 25 patients with idiopathic PAP(iPAP).