Ion confinement and separation using asymmetric electrodynamic fields in structures for lossless ion manipulations.

Rationale: TW-SLIM ion mobility separations have demonstrated exceptional resolution by leveraging long paths with minimal loss. All previously reported experiments have used electrode surfaces which are mirrored to generate symmetrically opposing electric fields for ion confinement. However, work with other planar ion optics indicates this may be unnecessary.

A Modular Variable Temperature FT-IMS Instrument Optimized for Gas-Phase Ion Chemistry Applications.

The latest iteration of modular, open-source rolled ion mobility spectrometers was characterized and tailored for heated ion chemistry experiments. Because the nature of ion-neutral interactions is innately linked to the temperature of the drift cell, heated IMS experiments explicitly probe the fundamental characteristics of these collisions. While classic mobility experiments examine ions through inert buffer gases, doping the drift cell with reactive vapor enables desolvated chemical reactions to be studied.

SLIM Tricks: Tools, Concepts, and Strategies for the Development of Planar Ion Guides.

Traveling wave ion mobility experiments using planar electrode structures (e.g., structures for lossless ion manipulation, TW-SLIM) leverage the mature manufacturing capabilities of printed circuit boards (PCBs).

Simultaneous Ion Swarm Profiling and Ion Mobility Measurement using Ion Cameras.

When operated as a standalone analytical device, traditional drift tube ion mobility spectrometry (IMS) experiments require high-speed, high-gain transimpedance amplifiers to record ion separations with sufficient resolution. Recent developments in the fabrication of charge-sensitive cameras (e.g.