Publications by authors named "Cullen E Buchanan"
Background: Underutilization of therapies to reduce ischemic risk in peripheral artery disease (PAD) persists.
Objectives: The purpose was to conduct an implementation trial of lipid management in vascular disease.
Methods: The OPTIMIZE PAD-1 (Implementation of Vascular Care Team to Improve Medical Management of PAD Patients) trial randomized patients with peripheral artery disease with low-density lipoprotein cholesterol (LDL-C) ≥70 mg/dL to management via a vascular care team including a clinical pharmacist and an algorithm of intensive lipid management to achieve goal LDL-C in 1 step vs usual care plus provider education.
An 86-year-old female with history of surgical aortic valve replacement presented with clinical signs of heart failure. Echocardiography revealed a reduction in left ventricular systolic function and severe bioprosthetic aortic valve dysfunction. This is the first reported case of valve-in-valve transcatheter aortic valve replacement with concomitant undermining iatrogenic coronary obstruction with radiofrequency needle procedure in a surgical bioprosthetic valve.
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- A 40-year-old woman with allergies and high eosinophil counts showed symptoms of heart failure and was diagnosed with restrictive cardiomyopathy and biventricular thrombi.
- The diagnosis was determined to be hypereosinophilic syndrome leading to eosinophilic myocarditis, also known as Loeffler's syndrome.
- The case emphasizes the importance of proper evaluation, diagnosis, and treatment strategies for managing hypereosinophilic syndrome and its cardiac complications.
Purpose: The purpose of this study was to determine whether increased intraluminal pressure is the damaging factor that reduces flow-mediated dilation (FMD) in young, healthy subjects after resistance exercise to maximal exertion.
Hypothesis: Attenuating the rise in brachial artery pressure during weight lifting by placing a blood pressure cuff on the upper arm prevents postexercise impairment of brachial artery FMD in sedentary individuals.
Methods: Nine sedentary individuals who exercise once a week or less and six exercise-trained individuals who exercise three times a week or more performed leg press exercise to maximal exertion on two separate occasions.