Publications by authors named "Culha G"

The study presents two imported malaria cases with a history of travel to malaria-endemic areas and replied late response to treatment. In the blood preparations of the first case, dot-shaped nucleus structures were identified in the erythrocytes, which looked different from the classical erythrocytic forms. In the SD-Pf/Pan test, bands were obtained for both P.

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Leishmaniasis causes significant morbidity and mortality worldwide. In our country, there has been a significant increase in the number of cases of leishmaniasis in the last decade. In our study, the effects of Hypericum thymbrifolium, Hypericum scabrum and Eryngium creticum plant extracts were tested on Leishmania major, Leishmania tropica and Leishmania infantum/donovani, which were clinically resistant by not responding to Glucantime® therapy.

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Article Synopsis
  • In Türkiye, malaria was eradicated in 2010, but there are still imported cases, leading researchers to compare two rapid diagnostic tests for malaria detection: SD-Pf/Pan and SD-Pf/Pv, against microscopy and RT-PCR.
  • The study involved testing blood samples from 66 suspected malaria cases, with microscopy and RT-PCR confirming 30 positive cases, while both rapid tests showed high sensitivity and specificity results, with SD-Pf/Pan performing slightly lower on some measures.
  • The findings suggest that both rapid tests can effectively diagnose malaria, but results should be validated with microscopy and RT-PCR for accurate diagnosis.
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is the species responsible for visceral leishmaniasis [(VL), kala-azar], which is observed sporadically mainly in pediatric age groups in the Aegean, Mediterranean and Central Anatolian regions of Türkiye. The aim of this study is to evaluate the diagnosis, clinic, laboratory results and treatments of four adult patients with VL who applied to our hospital. The patients were referred to our hospital to investigate hematological malignancy.

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Purpose Of Review: The aim of this narrative review is to evaluate the current available literature on urinary outcomes following cryotherapy and high-intensity focused ultrasound (HIFU) for localized prostate cancer (PCa).

Recent Findings: The available literature is heterogeneous in terms of intervention modalities and assessment of urinary outcome measures. Nevertheless, ultra-minimally invasive treatments seem to provide good urinary outcomes.

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Leishmaniasis is a parasitic infection caused by an obligate intracellular protozoon transmitted by infected sand flies. Cutaneous leishmaniasis (CL) is a skin disease known in our country as oriental sore, which heals, leaving a scar in place, mainly on the skin and sometimes in the mucous membrane. Demonstration of the parasite in chronic CL is difficult.

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Background: We report a nosocomial outbreak caused by Burkholderia cepacia that occurred among six patients admitted in the medical and surgical intensive care unit between 04 March 2019 and 02 April 2019 in Istanbul, Turkey.

Methods: The outbreak investigation was launched on 11 March 2019 five days after the detection of B. cepacia in four different patients.

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Leishmaniasis is a protozoan parasitic disease transmitted to humans by infected female sand flies. Turkey has received more than three million immigrants from Syria because of the civil war and political instability. This study reported cases of two patients, who were from Syria and lived in Hatay, with cutaneous leishmaniasis and mucosal involvement.

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Acanthamoeba species are free-living amoebae isolated from many ecological areas such as swimming pools, dams, lakes, soil, and air filters. These amoebae are usually causing granulomatous amebic encephalitis and amebic keratitis in immunosuppressive individuals. In this study, the reproductive potential and morphological changes determined of Acanthamoeba castellanii trophozoite and cyst forms exposed to three different active substances derived from benzothiazole.

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Background: Clinically, cutaneous leishmaniasis (CL) can be confused with granulomatous diseases and skin cancers, and it may lead to erroneous diagnosis and treatment. Diagnosis based and histopathology can have some difficulties due to low number of parasites, especially in chronic CL cases. We aimed to emphasize the necessity of considering CL in the differential diagnosis for cases of granulomatous diseases and basal cell carcinoma, particularly in areas where CL is endemic.

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Article Synopsis
  • The World Health Organization estimates that around one billion people are at risk for leishmaniasis, with about one million cases of cutaneous leishmaniasis (CL) and 300,000 cases of visceral leishmaniasis (VL) reported annually, resulting in roughly 20,000 deaths from VL each year.
  • In Turkey, about 2,500 cases of CL, primarily caused by Leishmania tropica, have been reported, with a significant increase in cases, particularly in the Mediterranean and Aegean regions, indicating a potential rise in infections.
  • The study aimed to identify antimony resistance genes in L.tropica by analyzing gene and protein expressions in both resistant and non-resistant strains, using methods
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Although asexual reproduction has been attributed to Leishmania species, genetic exchange has recently been demonstrated, which helped emerging of hybrid isolates. Situated on the crossroads between three continents, Leishmania hybrids may be present in Turkey. In Turkey, visceral leishmaniasis caused by Leishmania infantum is less common, while cutaneous leishmaniasis (CL) caused by Leishmania tropica and L.

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Objective: and are the species causing cutaneous Leishmaniasis (CL) in Turkey. There was a wave of immigration due civil war in Syria in 2011. Migration from Syria, where CL is endemic, to other countries is thought to affect the number of CL cases and species diversity.

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Leishmaniasis is a parasitic disease that is transmitted to humans by the bites of infected female phlebotomine sandflies. In the diagnosis of cutaneous leishmaniasis (CL), in the smear samples, the demonstration of the parasite by microscope remains a gold standard method. However, it becomes difficult to diagnose the parasite since the number of amastigotes in chronic cases with a lesion of one year or longer is very low.

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Objective: Cases with imported malaria have increased complication and mortality rates because of delayed diagnosis and treatment in non-endemic countries. This study aimed to investigate the incidence and clinical features of imported malaria in our clinic during the past 10 years.

Methods: This retrospective study included 75 cases diagnosed as having imported malaria in our clinic between January 2008 and December 2017.

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Objective: Medical questionnaires, which enable collection, comparison and analysis of appropriate data as a means of written communication between a patient and a doctor, must be easily readable, and understandable. Here, we measure the readability and understandability of questionnaires used in andrology and examine the relationship between the educational status of the patients and the understandability of the forms.

Material And Methods: Seven questionnaires (SHIM, AIPE, IIEF, MSHQ-EjD, PEDT, NIH-CPSI and IPSS) used to diagnose andological diseases were selected from the European Association of Urology guidelines.

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Leishmaniasis, seen in tropical and subtropical regions, is an infectious disease caused by the protozoan parasite Leishmania species. There are three main forms of leishmaniasis: cutaneous, mucocutaneous and visceral leishmaniasis. Cutaneous leishmaniasis (CL) has become an increasing problem as the number of travels around the world increases and people go to work in endemic areas.

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Article Synopsis
  • Malaria remains a significant public health issue, affecting millions annually, with 300-350 million exposed and 1.5-2.7 million deaths each year, mainly exacerbated by increased global population movements.
  • The study focused on male patients aged 25-60 from Hatay Province, many having worked in malaria-endemic regions like Sudan and Nigeria, highlighting a rise in imported malaria cases, particularly Plasmodium falciparum.
  • Findings emphasize the necessity of malaria prophylaxis for travelers to endemic areas and the need for awareness of imported malaria cases in public health efforts.
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Objective: To report isolation of Leishmania major strains obtained from 18 Turkish autochthonous cutaneous leishmaniasis (CL) patients infected with L. major between 2011 and 2014.

Methods: Initial diagnosis relied on microscopy and culture in enriched medium, prepared by adding specific amounts of liver extract, protein and lipid sources to NNN medium.

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Introduction: Healthcare-associated infections (HAIs) are important causes of morbidity and mortality, especially in critically ill patients in intensive care units. The aim of this study was to assess the rate and distribution of HAIs, pathogens, and antimicrobial susceptibility patterns in a newly opened pediatric intensive care unit (PICU).

Methodology: The infection control team detected and recorded HAI cases according to the Centers for Disease Control and Prevention's criteria in the PICU of Marmara University Pendik Training and Research Hospital over a four-year period following its opening.

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Background: Cutaneous leishmaniasis (CL) is endemic in Southeastern Anatolia, mainly in Sanliurfa and Hatay provinces, and the causative agents are mostly Leishmania tropica and less frequently L. infantum. Here, we report the first MALDI-TOF analyses of Leishmania promastigotes obtained from the cultures of two CL cases from Osmaniye and Hatay provinces who were initially diagnosed by microscopy, culture and identified as L.

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Leishmaniasis recidiva cutis (LRC) is an unusual form of acute cutaneous leishmaniasis. Herein, we present a case of LRC of the lips mimicking granulomatous cheilitis. An 8-year-old, Syrian child admitted with a swelling and disfigurement of his lips for 4 years.

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Article Synopsis
  • In Sanliurfa, CL cases are primarily caused by Leishmania tropica, but three new cases were identified due to L. major, including two local and one imported case.
  • This is the first report of L. major causing autochthonous CL in Sanliurfa, highlighting the need for public health measures and further research to understand the vectors and reservoirs for this parasite. *
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