PdMo Bimetallene Coupled with MXene Nanosheets as Efficient Bifunctional Electrocatalysts for Formic Acid and Methanol Oxidation Reactions.

In this study, we demonstrate a facile soft chemistry strategy for the growth of two-dimensional (2D) ultrathin PdMo bimetallene tightly coupled with TiCT MXene nanosheets (PdMo/TiCT) using a robust stereoassembly process. The 2D PdMo bimetallene offers numerous unsaturated Pd atoms and simultaneously induces combined bimetallic alloy and strain effects, while the TiCT matrix effectively optimizes the electronic structure of PdMo bimetallene via a face-to-face interface interaction and guarantees exceptional electrical conductivity. As a consequence, the newly designed PdMo/TiCT nanoarchitecture expresses remarkable electrocatalytic properties for the formic acid and methanol electro-oxidation, in terms of large electrochemically active surface areas, ultrahigh catalytic activity, strong antipoisoning ability, and dependable long-term stability, all of which are better than those of conventional Pd nanoparticle catalysts supported by TiCT and carbon matrices.

Facilitating interface charge transfer via constructing NiO/NiCoO heterostructure for oxygen evolution reaction under alkaline conditions.

Designing high-activity electrocatalysts to enhance the slow multielectron-transfer process of the oxygen evolution reaction (OER) is of great importance for hydrogen generation. Here, we employ hydrothermal and subsequent heat-treatment strategies to acquire nanoarrays-structured NiO/NiCoO heterojunction anchored Ni foam (NiO/NiCoO/NF) as efficient materials for catalyzing the OER in an alkaline electrolyte. Density functional theory (DFT) results demonstrate that NiO/NiCoO/NF exhibits a smaller overpotential than those of single NiO/NF and NiCoO/NF owing to interface-triggered numerous interface charge transfer.

Exosome-mediated circTTLL5 transfer promotes hepatocellular carcinoma malignant progression through miR-136-5p/KIAA1522 axis.

Background: Exosomes have been recognized as messengers for intercellular communication in tumor microenvironment. Exosomal circRNAs are reported to be important in tumors. Here, this study identified the potential function of exosomal circular RNA tubulin tyrosine ligase like 5 (circTTLL5) in hepatocellular carcinoma (HCC) progression.

Interfacial engineering of worm-shaped palladium nanocrystals anchored on polyelectrolyte-modified MXene nanosheets for highly efficient methanol oxidation.

The development of high-efficiency methanol oxidation electrocatalysts with acceptable costs is central to the practical use of direct methanol fuel cell. In this work, a convenient interfacial engineering strategy is developed to the design and construction of quasi-one-dimensional worm-shaped palladium nanocrystals strongly coupled with positively-charged polyelectrolyte-modified TiCT MXene (Pd NWs/PDDA-MX) via the direct electrostatic attractions. Because of the intriguing structural features including ultrathin-sheet nature, homogeneous Pd dispersion, numerous grain boundaries, strong electronic interaction, and high metallic conductivity, the as-fabricated Pd NWs/PDDA-MX hybrid shows superior electrocatalytic performance with a large electrochemically active surface area of 105.

Polyelectrolyte-Induced Stereoassembly of Grain Boundary-Enriched Platinum Nanoworms on TiCT MXene Nanosheets for Efficient Methanol Oxidation.

Direct methanol fuel cells with high energy conversion efficiency and low hazard emissions have aroused great attention from both academic and industrial communities, but their large-scale commercial application has been blocked by high costs as well as short lifespan of the anode Pt catalysts. Here, we demonstrate a simple and scalable noncovalent strategy for the synthesis of quasi-one-dimensional (1D) Pt nanoworms grown on poly(diallyldimethyl-ammonium chloride) (PDDA)-functionalized TiCT nanosheets as anode catalysts for methanol electrooxidation. Interestingly, the introduction of PDDA on TiCT nanosheets can not only effectively adjust their surface charge property to strengthen the electrostatic interaction between metal and support but also induce the stereoassembly of worm-shaped Pt nanocrystals with abundant catalytically active grain boundaries, which enable the resulting hybrid to express high electrocatalytic activity, remarkable durability, and strong antipoisoning ability for methanol electrooxidation, which are better than those of the traditional Pt nanoparticle electrocatalysts loaded on carbon black, carbon nanotubes, reduced graphene oxide, and MXene matrixes.

Graphene Nanoarchitectonics: Recent Advances in Graphene-Based Electrocatalysts for Hydrogen Evolution Reaction.

Under the double pressures of both the energy crisis and environmental pollution, the exploitation and utilization of hydrogen, a clean and renewable power resource, has become an important trend in the development of sustainable energy-production and energy-consumption systems. In this regard, the electrocatalytic hydrogen evolution reaction (HER) provides an efficient and clean pathway for the mass production of hydrogen fuel and has motivated the design and construction of highly active HER electrocatalysts of an acceptable cost. In particular, graphene-based electrocatalysts commonly exhibit an enhanced HER performance owing to their distinctive structural merits, including a large surface area, high electrical conductivity, and good chemical stability.

Effects of nebulized high-dose budesonide on moderate-to-severe acute exacerbation of asthma in children: a randomized, double-blind, placebo-controlled study.

Background And Objective: The efficacy of inhaled corticosteroids (ICS) in asthma exacerbation are yet to be clarified. The aim of this study was to investigate the efficacy of nebulized ICS in children with moderate-to-severe acute exacerbation of asthma in an emergency room setting in order to elucidate the potential use of ICS as the first-line therapy in the management of acute exacerbation of asthma.

Methods: This was a prospective, randomized, double-blind, placebo-controlled study.

[The efficacy of nebulized budesonide in acute moderate to severe exacerbations of asthma in children].

Objective: To evaluate the effect of nebulized budesonide (BUD) in acute moderate to severe exacerbations of asthma in children.

Methods: Forty children, 5 to 15 years of age, with acute moderate to severe attacks of asthma, were randomized into BUD group and control group, receiving nebulized 0.5% salbutamol (150 µg/kg) + 0.