Experimental infection of Marmota monax with a novel hepatitis A virus.

To establish an animal model for the newly identified Marmota Himalayana hepatovirus, MHHAV, so as to develop a better understanding of the infection of hepatitis A viruses. Five experimental woodchucks (Marmota monax) were inoculated intravenously with the purified MHHAV from wild woodchuck feces. One animal injected with PBS was defined as a control.

Identification of a Novel Enterovirus Species in Rhesus Macaque in China.

Recent studies of Enterovirus (EV) in nonhuman primates (NHPs), which could act as a source of future emerging human viral diseases, have boosted interest in the search for novel EVs. Here, a highly divergent strain of EV, tentatively named SEV-gx, was identified by viral metagenomic analysis from stool samples of rhesus macaques in China. In total, 27 of 280 (9.

[Metagenomic Analysis of Wild Rhesus Monkey Virome in Longhu Mountain in Guangxi Area, China].

Several viruses have been found in non-human primates, among which some are pathogenic to humans. To further characterize the spectrum of viruses present in wild rhesus monkeys, MiSeq high-throughput sequencing were used to analyze 280 fecal samples collected from Guangxi, China. A total of 23,372,679 reads were obtained, of which 4,641 were annotated to 27 viral families or subfamilies, including five vertebrate viruses families(78.

A novel hepatovirus identified in wild woodchuck Marmota himalayana.

Hepatitis A virus (HAV) is a hepatotropic picornavirus that causes acute liver disease worldwide. Here, we report on the identification of a novel hepatovirus tentatively named Marmota Himalayana hepatovirus (MHHAV) in wild woodchucks (Marmota Himalayana) in China. The genomic and molecular characterization of MHHAV indicated that it is most closely related genetically to HAV.