A selective N,N-dithenoyl-rhodamine based fluorescent probe for Fe detection in aqueous and living cells.

A novel N,N-dithenoyl-rhodamine based fluorescent and colorimetric Fe probe 1 was designed and synthesized by only one step from Rhodamine B hydrazide and 2-thiophenecarbonyl chloride. The structure of probe 1 was characterized by H NMR/C NMR spectroscopy, IR spectroscopy, and HRMS spectrometry. Accompanying with significant changes in visual color and fluorescent spectrum, probe 1 displayed good sensitivity for Fe with an abroad pH span.

Exposure to HBCD promotes adipogenesis both in vitro and in vivo by interfering with Wnt6 expression.

Hexabromocyclododecane (HBCD) is a widely used brominated flame retardant, and a ubiquitous environmental contaminant. However, effects and mechanisms underlying HBCD and the development of obesity remain largely unknown. Here, we investigated the effects and underlying mechanisms of HBCD on adipogenesis.

Suffering a Loss Is Good Fortune: Myth or Reality?

We sometimes decide to take an offered option that results in apparent loss (e.g., unpaid overtime).

The hidden opportunity cost of time effect on intertemporal choice.

An interesting phenomenon called "hidden opportunity cost of time effect" was detected in intertemporal choices. The majority of our participants preferred the smaller but sooner (SS) option to the larger but later (LL) option if opportunity cost was explicit. However, a higher proportion of participants preferred the LL to SS option if opportunity cost was hidden.

[Cochlear implantation with pericanal electrode insertion technique].

Objective: To investigate the surgical technique of the pericanal electrode insertion technique for ies cochlear implantation.

Method: Forty cases of sensorineural deafness were subjected to the ies cochlear implants. Cochleostomy was performed through the external auditory canal with a microdrill anterior to the round window.

[Effects of jingtian tongmai recipe on atherosclerotic plaque in rabbits].

Objective: To evaluate the inhibiting effects of Jingtian Tongmai Recipe (JTTMR) in different dosages on atherosclerotic plaque using the arteriosclerosis rabbit model induced by high cholesterol diet supplemented with immunological injury.

Methods: Fifty-four healthy New Zealand rabbits were randomly divided into six groups: the normal control group, the model group, the Xuezhikang (XZK) treated group and the three JTTMR treated groups treated respectively with low (1.29 g/kg/day), medium (2.

[Analysis of abnormality of the middle ear in infant and young children].

Objective: To discuss the diagnosis of middle ear abnormality in infants and young children.

Methods: To analyze retrospectively the data of audiology (including ABR, tympanometry) and CT scanning in 31 infants and young children who presented middle ear abnormality.

Results: Wave I latencies of ABR were delayed in 38 of 62 ears and not delayed in 15 ears, but CT scanning showed high density in 6 ears of these 15 ears.

[Comparative study on the acute toxicity of pulmonary caused by nanosized and microsized powders of silicon dioxide].

Objective: To compare the acute pulmonary toxicities of nanosized and microsized silicon dioxide particles.

Methods: All 125 healthy male Wistar rats were divided into 25 groups randomly according to the weight. Experimental animals were exposed to microsized SiO2 at the doses of 100 mg/m3 (group A) and 300 mg/m3 (group B), and to the nanosized SiO2 at the same dose levels (group A' and B') by inhalation for 2 hours.

[Comparative study of the effect on oxidative damage in rats inhaled by nano-sized and micro-sized silicon dioxide].

Objective: To compare the changes of oxidative damage in rats inhaled by nano-sized and micro-sized silicon dioxide.

Methods: 36 male rats were randomly divided into two control groups and four experimental groups which was inhaled by nano-sized and micro-sized silicon dioxide respectively at the concentration of 300 mg/m3 for 2 hours and the activities of SOD, CAT and GSH-Px and the contents of H2O2, GSH and MDA of the liver, kidney, brain were determinated 24h and 48h after inhalation.

Results: The contents of H2O2 in all organs in nano-sized groups increased significantly while increased in micro-size groups only in liver and kidney at 24h and in brain at 48h.

[Effects of perfluorooctane sulfonate on Glu, PKC and PKA activities in mouse brain].

Objective: To study the effects of perfluorooctane sulfonate (PFOS) on contents of glutamate and activity of protein kinase C (PKC) and A (PKA) and ultrastructure injury in the brain of male mice and to explore the mechanism of neurotoxicity and patho-alteration resulted from PFOS.

Methods: 44 male mice were randomly divided into four groups, who were respectively orally given 0, 5, 10, 20 mg/kg PFOS for 10 days. The Glu consents in the brain of the mice was measured with spectrophotometer and protein kinases activity were measured with non-radioactive assay of protein kinase and the changes of cerebral cortex ultrastructure were observed.

[Comparative study of effects of nanosized and microsized silicon dioxide dust on mouse embryos].

Objective: To compare the effect of mouse embryonic toxicity between nanosized and microsized dioxide silicon, and detect the point mutation of Cx32 and Cx40 genes after the interference with nm-SiO2 and microm-SiO2 on pregnant mice.

Methods: Twenty-five male mice in 5 groups (control, microm-SiO2 50mg/m3, microm-SiO2 200mg/m3, nm-SiO2 50mg/m3, nm-SiO2 200mg/m3 groups) were treated through respiration from E0 to E17, study pregnant mice weights change trend, take out the embryos on E18, observe embryonic development circumstance and detect the point mutation of Cx32 and Cx40 genes with general PCR, PCR-SSCP methods.

Results: Pregnant mice weights in all interfered groups were lower than that in control group on E18.

[Effects of nonnutritive sucking on gastric emptying and gastroesophageal reflux in premature infants].

Objective: Although nonnutritive sucking (NNS) during tube feeding has some benefits on the physiology and development of premature infants, the effect on gastrointestinal function remains controversial. The aim of the study was to evaluate the effects of NNS on the gastric emptying and gastroesophageal reflux (GER) in premature infants.

Methods: Thirty eight healthy appropriate-for-gestational-age premature infants (birth weight ranged from 1050 g to 1790 g, gestational age ranged from 28 weeks to 35 weeks) accepting intermittent nasogastric feeding (INGF) were randomized into NNS group and N-NNS group according to INGF with and without NNS and fed with the same milk formula.

[Adjuvant treatment of anisodamine to acute serous otitis media].

Objective: To evaluate the adjuvant treatment of anisodamine to acute serous otitis media.

Method: Sixty-one acute otitis media patients were divided randomly into two groups. Group A with 30 patients were treated with 1% ephedrine nosedrop, antibiotic and antihistamine.

[Effects of intermittent nasogastric feeding with nonnutritive sucking on nutrient and gastrointestinal tract transit time in premature infants].

Objective: To evaluate the effects of nonnutritive sucking (NNS) on the nutrient intake, physical growth, feeding-related complications and whole gastrointestinal transit time (WGTT) in premature infants.

Methods: Thirty eight healthy appropriate for gestational age premature infants (birth weights ranged from 1 050 g to 1 790 g) accepting intermittent nasogastric feeding (INGF) were randomized into NNS group and N-NNS group according to INGF with and without NNS and fed with the same milk formula. The following data were collected and recorded, the physical growth parameters (e.

[Study on distortion product otoacoustic emissions and expanded high frequency audiometry in noise exposure workers].

Objective: To analyse the relationship of distortion product otoacoustic emissions(DPOAE), conventional pure tone audiometry and expanded high frequency audiometry, and discuss the originated mechanism of DPOAE and value in early diagnosis and detection noise-induced deafness.

Method: DPOAE, conventional pure tone audiometry and expanded high frequency audiometry were performed in 42 young adults with normal hearing of control group and 20 noise exposure workers of test group. DPOAE amplitudes, conventional pure tone hearing thresholds and expanded high frequency hearing thresholds were compared.