Publications by authors named "Cuiping Xun"
Cell Death Discov
October 2024
Article Synopsis
- Type I interferon (IFN-I) is important for fighting viral infections and managing autoimmune diseases by regulating the expression of interferon-stimulated genes (ISGs).
- This study shows that PCGF3 acts as a suppressor of the antiviral response by inhibiting ISG expression, meaning that less PCGF3 allows for a stronger immune response to IFN-I.
- The research also found that lower levels of PCGF3 in patients with dermatomyositis are linked to higher ISG expression, suggesting that PCGF3 plays a key role in controlling immune responses in disease conditions.
