Comparison of the effectiveness of different corneal curvature measurement methods for IOL implantation in traumatic aphakic eyes with corneal injury.

Background/aim: To assess the refractive outcomes of secondary intraocular lenses (IOL) in patients with traumatic aphakic eyes with corneal penetrating injury and compare different corneal curvature measurement methods.

Methods: Patients with unilateral penetrating eye injuries underwent corneal wound repair and cataract extraction, followed by secondary IOL implantation. Corneal curvature measurements were taken on the contralateral healthy eye (Group A), from the affected eye before removing corneal sutures (Group B), or after suture removal (Group C).

Accuracy of 10 MHz ultrasonography for evaluation of posterior lens capsule in traumatic cataract.

Purpose: To investigate the performance of 10 MHz ultrasonography in detecting posterior lens capsule defects before traumatic cataract surgery.

Methods: This retrospective analysis includes patients with traumatic cataracts who underwent cataract surgery. Preoperative 10 MHz ultrasonography was performed to evaluate whether the posterior lens capsule was defective or intact, and the results were compared to the intraoperative findings.

A comparative study of genotyping and antimicrobial resistance between carbapenem-resistant and isolates at a tertiary pediatric hospital in China.

Background: Carbapenem-resistant (CRKP) clinical isolations have rapidly increased in pediatric patients. To investigate a possible health care-associated infections of CRKP in a tertiary pediatric hospital, the circulating clones and carbapenem-resistant pattern between CRKP and carbapenem-resistant (CRAB) isolates were compared to classify their epidemiological characteristics. The results will help to identify the epidemic pattern of the CRKP transmission in the hospital.

Viral etiology of acute respiratory tract infection among children under 5 years of age in Kunming City, China: a matched case-case-control study.

Aims: Nucleic acid-based molecular techniques in current laboratory practice allow the identification of a broad range of respiratory viruses. However, due to asymptomatic carriage, the detection of viruses in the respiratory tract does not necessarily indicate disease. The study aimed to investigate infections of different viruses that colonize the airways, the viral combinations in coinfection, and the viral association with the occurrence of either upper respiratory tract infection (AURTI) or lower respiratory tract infection (ALRTI) in children.

[Spatial Characterization of Stable Isotope Composition of Organic Carbon from Farmland Soils in Chongqing].

Soil was sampled from 182 profiles in typical farmlands of Chongqing and analyzed for the stable carbon isotope composition of organic matter (C). The results showed that the values of C for each soil profile were gradually increasing with increasing soil depth, and the mean values were (-23.63±1.

[A pedigree study of laryngo-onycho-cutaneous syndrome with a novel mutation on LAMA3 gene].

To detect genetic mutations in a case of laryngo-onycho-cutaneous syndrome, and to explore the possible molecular biological pathogenic causes. With informed consent, the family clinical data of the child with laryngo-onycho-cutaneous syndrome were collected, peripheral blood of the protester and his parents was collected and DNA was extracted, and gene detection was performed by high-throughput sequencing method. Sanger sequencing was used to verify and analyze the mutation sites of the probs and their families.

Real-time Prediction of the Daily Incidence of COVID-19 in 215 Countries and Territories Using Machine Learning: Model Development and Validation.

Background: Advanced prediction of the daily incidence of COVID-19 can aid policy making on the prevention of disease spread, which can profoundly affect people's livelihood. In previous studies, predictions were investigated for single or several countries and territories.

Objective: We aimed to develop models that can be applied for real-time prediction of COVID-19 activity in all individual countries and territories worldwide.

Improved Automated Foveal Avascular Zone Measurement in Cirrus Optical Coherence Tomography Angiography Using the Level Sets Macro.

Purpose: To evaluate automated measurements of the foveal avascular zone (FAZ) using the Level Sets macro (LSM) in ImageJ as compared with the Cirrus optical coherence tomography angiography (OCTA) inbuilt algorithm and the Kanno-Saitama macro (KSM).

Methods: The eyes of healthy volunteers were scanned four times consecutively on the Zeiss Cirrus HD-OCT 5000 system. The FAZ metrics (area, perimeter, and circularity) were measured manually and automatically by the Cirrus inbuilt algorithm, the KSM, and the LSM.

Retrospective analysis of the accuracy of predicting the alert level of COVID-19 in 202 countries using Google Trends and machine learning.

Background: Internet search engine data, such as Google Trends, was shown to be correlated with the incidence of COVID-19, but only in several countries. We aim to develop a model from a small number of countries to predict the epidemic alert level in all the countries worldwide.

Methods: The "interest over time" and "interest by region" Google Trends data of Coronavirus, pneumonia, and six COVID symptom-related terms were searched.

Retrospective analysis of the possibility of predicting the COVID-19 outbreak from Internet searches and social media data, China, 2020.

The peak of Internet searches and social media data about the coronavirus disease 2019 (COVID-19) outbreak occurred 10-14 days earlier than the peak of daily incidences in China. Internet searches and social media data had high correlation with daily incidences, with the maximum r > 0.89 in all correlations.

Reliability of foveal avascular zone metrics automatically measured by Cirrus optical coherence tomography angiography in healthy subjects.

Purpose: To investigate the reliability of the foveal avascular zone (FAZ) metrics automatically measured using Cirrus optical coherence tomography angiography (OCTA) embedded algorithm compared to human manual measurement.

Methods: Thirty-five eyes of 35 healthy subjects were enrolled and scanned four times continuously on Zeiss Cirrus HD-OCT 5000. The FAZ metrics (area, circularity and perimeter) of the superficial capillary plexus were measured automatically using the embedded tool and manually measured by the two independent observers using ImageJ.

[Detection of gene expression alteration of myeloma cells treated with arsenic trioxide].

Objective: To investigate the effect of arsenic trioxide on multiple myeloma (MM) cell gene expression and explore the molecular mechanism of arsenic trioxide therapy for MM.

Methods: U266 cells were divided into two groups, group A as control group and group B as test group. Cells were cultured for 48 hours, and total RNA and mRNA were extracted.

The density distributions of the counterions and the coions confined in two similarly charged plates.

By using the field-theoretic method, we established a unified systematic formulation of a model of counterions and coions confined in two similarly charged plates, and calculated the density distributions of counterions and coions with various coupling parameters by the two methods: Poisson-Boltzmann (PB) approach and the strong coupling (SC) theory, respectively. We also performed Monte Carlo simulations, and obtained the density distributions of counterions and coions with several different coupling parameters. Comparing our theoretical results with those from Monte Carlo simulation, we find that the PB approach is valid when the coupling parameter Xi is smaller than 1, but, as Xi > or = 1, the results by the PB approach deviate from the corresponding Monte Carlo simulation data, and the deviation gets larger with the coupling parameter increasing.