Publications by authors named "Cuige Zuo"
Scope: Mycotoxins co-contamination of agricultural products poses a serious threat to human and animal health, especially hepatic dysfunction. Zearalenone (ZEN), deoxynivalenol (DON), and aflatoxin B1 (AFB1) are three commonly co-occurring mycotoxins. This study is to determine whether lycopene (LYC) can alleviate hepatic toxicity induced by the co-occurrence of ZEN, DON, and AFB1 in mice.
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- Multiple mycotoxins, including zearalenone (ZEN), deoxynivalenol (DON), and aflatoxin B1 (AFB1), can accumulate in the food chain, posing health threats to humans and animals by causing toxicity in the jejunum.
- The study tested lycopene (LYC) as a potential treatment to reduce jejunal damage in mice exposed to these toxins, showing that LYC improved intestinal structure and increased protective protein levels.
- Results indicated that LYC mitigated oxidative stress and mitochondrial damage caused by the mycotoxins and potentially reduced the risk of ferroptosis, a form of cell death associated with this kind of damage.