Genome-Wide Analysis Elucidates the Roles of Genes in Different Abiotic Stresses and Growth and Development Stages in the Peanut ( L.).

The lateral organ boundaries domain () genes, as the plant-specific transcription factor family, play a crucial role in controlling plant architecture and stress tolerance. However, the functions of genes in the peanut plant ( L.) remain unclear.

The PGC-1α/ERRα/ULK1 pathway contributes to Perioperative neurocognitive disorders by inducing mitochondrial dysfunction and activating NLRP3 inflammasome in aged mice.

Perioperative neurocognitive disorders (PND) are intractable, indistinct, and considerably diminish the postoperative quality of life of patients. It has been proved that Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) was involved in neurodegenerative diseases by regulating mitochondrial biogenesis. The underlying mechanisms of PGC-1α and Nod-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome in PND are not well understood.

Understanding the factors of wearable devices among the patients with thyroid cancer: A modified UTAUT2 model.

Wearable devices hold promising prospects on a global scale, including in China. Thyroid cancer prevalence is notably high in China.This purpose of this researchwas to provide an updated theoretical model for assessing Chinese thyroid cancer patients' intentions towards wearable devices, based on the UTAUT2 framework, and to ascertain the factors that have an impact on these intents.

Transcriptomic analysis reveals the regulatory mechanisms of messenger RNA (mRNA) and long non-coding RNA (lncRNA) in response to waterlogging stress in rye (Secale cereale L.).

Background: Waterlogging stress (WS) negatively impacts crop growth and productivity, making it important to understand crop resistance processes and discover useful WS resistance genes. In this study, rye cultivars and wild rye species were subjected to 12-day WS treatment, and the cultivar Secale cereale L. Imperil showed higher tolerance.

GhHDZ76, a cotton HD-Zip transcription factor, involved in regulating the initiation and early elongation of cotton fiber development in G. hirsutum.

In this study, the whole HD-Zip family members of G. hirsutum were identified, and GhHDZ76 was classified into the HD-Zip IV subgroup. GhHDZ76 was predominantly expressed in the 0-5 DPA of fiber development stage and localized in the nucleus.

Genome-Wide Analysis Elucidates the Roles of / Genes Reveals the Function of () in Cold Stress in .

This study identified 13 / members in through bioinformatics methods and divided them into three subgroups by phylogenetic tree analysis. Motif and gene structure analysis showed that the genes in this family were highly conserved. Promoter -acting element analysis found that the promoters of / contained a large number of -acting elements in response to growth and development and abiotic stress.

Carbohydrate metabolism and cytology of S-type cytoplasmic male sterility in wheat.

Introduction: Cytoplasmic male sterility (CMS) is an important tool for hybrid heterosis utilization. However, the underlying mechanisms still need to be discovered. An adequate supply of nutrients is necessary for anther development; pollen abortion would occur if the metabolism of carbohydrates were hampered.

[Inhibition of Ferulic Acid on U937 Cell Growth and Its Related Mechanism].

Objective: To investigate the effects of ferulic acid (FA) on proliferation, apoptosis and Toll-like receptor 4 (TLR4)/nuclear factor-κB (NF-κB) signaling pathway of human acute myeloid leukemia (AML) U937 cells.

Methods: Different concentrations of FA (0、10、25、50、100、200 μmol/L) was used to treat human AML cell lines Kasumi-1, HL-60, and U937 cells respectively for 24 h. The cell survival rate was detected by cell counting kit-8 method, and the 50% inhibitory concentration (IC) of each cell line was calculated.

Application of Dual-Source CT Using Iterative Reconstruction Technology Combined with CT-FFR Parameters in the Diagnosis of Coronary Heart Disease.

Background And Objective: In order to achieve early detection of myocardial ischemia and improve the diagnosis of coronary heart disease (CHD), it is necessary to find a convenient, non-invasive and effective examination method. This study aimed to explore the application value of dual-source computed tomography (CT) by using advanced modeled iterative reconstruction (ADMIRE) combined with computed tomography-fractional flow reserve (CT-FFR) technique in CHD, which provides imaging basis for early diagnosis of CHD and myocardial ischemia.

Methods: Seventy-five CHD patients were examined by coronary computed tomography angiography (CCTA).

Circ_0084188 promotes colorectal cancer progression by sponging miR-654-3p and regulating kruppel-like factor 12.

To investigate the biological role and mechanism of circ_0084188 in colorectal cancer (CRC). Real-time quantitative polymerase chain reaction and western blot assay were used to detect RNA levels and protein levels in CRC cell lines (HCT116 and SW480), respectively. Cell proliferation was evaluated by Cell Counting Kit-8 assay, 5-ethynyl-2'-deoxyuridine assay, and colony formation assays.

Aptamer-mediated hollow MnO for targeting the delivery of sorafenib.

Sorafenib (SRF) presents undesirable effects in clinical treatment, due to the lack of targeting, poor water solubility, and obvious side effects. In this study, we constructed a novel nanodrug carrier system for accurate and efficient delivery of SRF, improving its therapeutic effects and achieving tumor-specific imaging. The hollow mesoporous MnO (H-MnO) nanoparticles equipped with target substance aptamers (APT) on the surface were used to load SRF for the first time.

Genome-wide analysis elucidates the roles of GhHMA genes in different abiotic stresses and fiber development in upland cotton.

The heavy metal-binding domain is involved in heavy metal transporting and plays a significant role in plant detoxification. However, the functions of HMAs are less well known in cotton. In this study, a total of 143 GhHMAs (heavy metal-binding domain) were detected by genome-wide identification in G.

[Advances of CRISPR/Cas9 activation system].

Gene editing technology has been a hotspot in the field of biotechnology. CRISPR/Cas systems are efficient gene editing tools because of its specificity, simplicity and flexibility, these features enabled the rapid application of CRISPR/Cas systems in a variety of organisms. Moreover, the combination of transcriptional activator with dead Cas protein can achieve specific regulation of gene expression at the transcription level, which has made important contributions to the development of biotechnology in medical and agriculture.

Review on the Effect of Exercise Training on Immune Function.

Exercise training is not only a necessary means to improve the level of exercise, but also an important means to improve the body's immunity. Different time, intensity, items, and forms of exercise training have different effects on the body's immune function. As a double-edged sword to improve the body's immune function, exercise training is a different reaction mechanism of different immune cells after exercise training.

β-catenin inhibitors ICG-001 and pyrvinium sensitize bortezomib-resistant multiple myeloma cells to bortezomib.

Although bortezomib (BTZ) displays efficacy in treating multiple myeloma (MM), BTZ resistance in MM patients has been reported. Meanwhile, treating BTZ resistant MM cells with β-catenin inhibitors have demonstrated the ability to reserve BTZ resistance. Thus, the present study aimed to investigate the synergistic effect of the β-catenin inhibitors, ICG-001 and pyrvinium (PP), with BTZ in the treatment of BTZ-resistant MM cells.

Quantitative Evaluation of Small Intestinal Hemorrhage Using Energy Spectrum CT Iodine-Water Map.

The objective of this research is to analyze the quantitative evaluation of human small intestinal bleeding by observing and analyzing animal experiments of small intestinal hemorrhage in rabbit models for the convenience of understanding the role of energy spectrum CT iodine-water diagram in animal experimental research of quantitative evaluation of small intestinal bleeding in rabbit models. Compared with the energy spectrum of iodine-water graph of a rabbit CT model, the present study studied the quantitative evaluation of small intestinal bleeding by using a rabbit model instead of human. According to the method mentioned above and the analysis of experimental data, the role of energy spectrum CT iodine-water map and the quantitative evaluation of human small intestinal bleeding have been understood.

Corrigendum to "CAMPO Precision128 Max ENERGY Spectrum CT Combined with Multiple Parameters to Evaluate the Benign and Malignant Pleural Effusion".

[This corrects the article DOI: 10.1155/2021/5526977.].

Genome-Wide Identification and Characterization of GhCOMT Gene Family during Fiber Development and Verticillium Wilt Resistance in Cotton.

Caffeic acid -methyltransferases (COMTs) play an essential role in lignin synthesis procession, especially in the plant's phenylalanine metabolic pathway. The content of COMT genes in cotton and the relationship between their expression patterns have not been studied clearly in cotton. In this study, we have identified 190 COMT genes in cotton, which were classified into three groups (I, II and III), and mapped on the cotton chromosomes.

First principles study on electronic properties and oxygen evolution mechanism of 2D bimetallic N-doped graphene.

Currently, the oxygen evolution reaction (OER) is constrained by complex four-electron transport, thus it is difficult to understand the catalytic mechanism. In this work, the electronic properties and catalytic performance of MM/NC (M = Mn, Fe, Co, Ni, Cu and Zn, random combination in pairs) is studied by density functional theory, the calculated results show that the overpotential of FeCu/NC is 0.88 V, which is used as the optimal catalyst to further study the OER reaction mechanism.

Three Types of Charged Ligands Based Carboxyl-Containing Iridium(III) Complexes: Structures, Photophysics, and Solution Processed OLED Application.

A novel family of three types of charged (0, -1, -2) ligands based phosphorescent iridium(III) complexes with different carboxyl-containing dianionic (-2) ligands have been synthesized. Their single-crystal structures show that all neutral complexes (, , and ) show a trans-N^N configuration between dianionic (-2) and monoanionic (-1) ligands, which is in contrast with the trans-N^C configuration in cationic complex , which has an interesting hydrogen bond in the solid state. Notably, shows higher luminescence efficiency and an obvious blue shift emission relative to those in , , and .

CAMPO Precision128 Max ENERGY Spectrum CT Combined with Multiple Parameters to Evaluate the Benign and Malignant Pleural Effusion.

The emergence of energy spectrum CT provides greater diagnostic value for clinical practice. Its advantage is that it can provide more functional imaging parameters and accurate image information for clinical practice, which represents a mainstream direction of CT technology development at present. This paper mainly studies the clinical trial of CAMPO Precision128 Max ENERGY spectrum CT combined with multiple parameters to evaluate the benign and malignant pleural effusion.

Tuning the Photophysical and Excited State Properties of Phosphorescent Iridium(III) Complexes by Polycyclic Unit Substitution.

Two novel N-embedded polycyclic units functionalized phosphorescent iridium(III) complexes ( and ) with substituents in different positions have been prepared. Complex bearing the substituent at the 3-position shows a distinct blue shift single-peak emission (524 nm) with a higher luminescence efficiency (Φ=42 %) and shorter emission lifetime (τ=282 ns) by comparison with 4-position substitution based complex (Φ=23 %, τ=562 ns), which exhibits a dual-peak emission (564 nm and 602 nm), and phosphorescence color can be tuned from green to yellow. In addition, DFT calculations demonstrate that unusual ligand-to-metal charge transfer (LMCT) excited state property can be found in , which is in contrast to metal-to-ligand charge transfer (MLCT) excited state character in .

Correlation analyses of thyroid-stimulating hormone and thyroid autoantibodies with differentiated thyroid cancer.

Purpose: To investigate the feasibilities and clinical values of thyroid-stimulating hormone (TSH) and thyroid autoantibodies in predicting differentiated thyroid cancer (DTC).

Methods: 500 patients with thyroid nodules who underwent surgery for the first time in our hospital from January 2014 to December 2016 were selected, including 250 patients definitely diagnosed pathologically with DTC and 250 patients definitely diagnosed with benign thyroid nodules after operation. Serum thyroglobulin antibody (TgAb), thyroid peroxidase antibody (TPOAb) and TSH levels before operation were evaluated in both groups.