Publications by authors named "Cui-yun Dou"
[Relationship between Quantitative Monitoring of WT1 Gene and Prognosis in Patients with Acute Leukemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2018
Objective: To investigate the exprassion of WT1 gene in patients with adult acute myeloid leukemia (AML) and its clinical significance.
Methods: Sixty-three newly diagnosed patients with acute myeloid leukemia were selected. Quantitative RT-PCR was used to detect the expression of WT1 gene in the 63 AML patients and 20 non-AML controls.
Aplastic anaemia (AA) is a life-threatening hematopoietic disorder characterized by hypoplasia and pancytopenia with increasing fat cells in the bone marrow (BM). The BM-derived mesenchymal stem cells (MSCs) from AA are more susceptible to be induced into adipogenic differentiation compared with that from control, which may be causatively associated with the fatty BM and defective hematopoiesis of AA. Here in this study, we first demonstrated that levamisole displayed a significant suppressive effect on the in vitro adipogenic differentiation of AA BM-MSCs.
View Article and Find Full Text PDFAcute immune thrombocytopenic purpura as adverse reaction to oral polio vaccine (OPV).
Hum Vaccin Immunother
August 2013
Article Synopsis
- A case was reported of an 82-day-old infant who developed acute immune thrombocytopenic purpura (ITP) after receiving the second dose of the oral polio vaccine (OPV).
- The infant, previously healthy and not on any medications, had a very low platelet count of 13×10(9)/L, with elevated platelet-associated IgG suggesting an immune response.
- After proper treatment, the infant recovered within 30 days, highlighting the need for awareness of potential thrombocytopenia linked to OPV, although it occurs less frequently compared to natural infections.