Publications by authors named "Cui-cui Ge"
Article Synopsis
- Alpinia oxyphylla (AOF) is an important medicinal fruit in China, studied for its potential benefits in addressing cognitive disorders related to type 2 diabetes mellitus (T2DM).
- Researchers isolated 24 compounds from AOF, including three new substances, identifying several that showed activity in inhibiting the enzyme BACE1, which is linked to T2DM-associated cognitive issues.
- Key compounds demonstrated neuroprotective effects against amyloid β damage in cells, with certain diarylheptanoids and sesquiterpenoids found to both inhibit BACE1 and modulate related protein expressions to mitigate cognitive decline.
Article Synopsis
- The study examines the costs of long spines in the rotifer species Brachionus forficula by comparing them to those with short spines.
- Results indicate that rotifers with long spines have longer juvenile and embryo stages but lower population growth rates and reproductive rates than those with short spines.
- Additionally, long-spined rotifers show reduced competition ability and lower starvation resistance, suggesting they expend more energy on spine development rather than reproduction and survival.
Recent studies have demonstrated that the crucial regulatory roles of long noncoding RNAs (lncRNAs) in tumorigenesis. Expression levels of several lncRNAs are abnormally up-regulated or down-regulated and play a primary role in colorectal cancer (CRC) cell tumorigenesis. However, the potential role and regulatory mechanisms of the novel human lncRNA, LINC00152, in CRC cells are poorly understood.
View Article and Find Full Text PDF[Effects of maternal exposure to nano-alumina during pregnancy on neurodevelopment in offspring mice].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
October 2013
Objective: To observe the effects of maternal exposure to nano-alumina during pregnancy on the neurodevelopment in offspring mice.
Methods: Female ICR mice began to be exposed to nano-alumina 10 d before mating, and the nano-alumina exposure lasted till offspring mice were born. All the female mice were randomly divided into 5 groups: solvent control group (saline), nano-carbon group (11.
[Changes of brain oxidative stress induced by nano-alumina in ICR mice].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
June 2011
Objective: To investigate the brain oxidative stress injury induced by nano-alumina particles in ICR mice.
Methods: Sixty male ICR mice were randomly divided into 6 groups: control group, solvent control group, 100 mg/kg micro-alumina particles group, 3 groups exposed to nano-alumina particles at the doses of 50, 100 and 200 mg/kg. The mice were exposed by nasal drip for 30 days.