Publications by authors named "Cui-Yun Zhu"
Clinical Immunophenotype at Disease Onset in Previously Healthy Patients With Cryptococcal Meningitis.
Medicine (Baltimore)
February 2016
Article Synopsis
- Cryptococcal meningitis (CM) is a serious global disease affecting both HIV-infected and previously healthy patients, yet the immune responses in previously healthy patients (PHPs) are not well understood.
- A study analyzing 41 CM patients found that PHPs had higher counts of certain immune cells compared to non-PHPs, but similar levels of inflammatory markers, aside from lower immunoglobulin A (IgA) in non-PHPs.
- Despite PHPs having a higher five-year mortality rate than non-PHPs (22% vs. 12.5%), this difference was not statistically significant; however, higher immunoglobulin G (IgG) levels in serum during the disease onset may indicate increased mortality