Publications by authors named "Cui-Ying Chu"
[Effect of Chidamide on the Killing Acitivity of NK Cells Targeting K562 Cells and Its Related Mechanism In Vitro].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
August 2020
Article Synopsis
- The study aims to examine how chidamide affects the ability of natural killer (NK) cells to kill K562 cancer cells and the underlying mechanisms involved.
- Researchers treated K562 cells with varying concentrations of chidamide and measured NK cell interactions using flow cytometry to analyze killing activity and marker expressions.
- Results indicated that chidamide enhances the sensitivity of NK cells toward K562 cells, possibly by increasing the expression of the ULBP2 marker, while it did not exhibit significant toxicity towards K562 cells.