Publications by authors named "Cui-Shan Huang"
Article Synopsis
- * In a study using rats with induced sarcopenia, icariin administration for 8 weeks resulted in improved muscle strength and increased muscle fiber size compared to a control group.
- * Icariin appears to work by enhancing myosin heavy chain expression in muscles and reducing specific proteins that lead to muscle degradation, highlighting its protective role against sarcopenia.
Objectives: Vascularization is an essential step in successful bone tissue engineering. The induction of angiogenesis in bone tissue engineering can be enhanced through the delivery of therapeutic agents that stimulate vessel and bone formation. In this study, we show that cucurbitacin B (CuB), a tetracyclic terpene derived from Cucurbitaceae family plants, facilitates the induction of angiogenesis
Methods: We incorporated CuB into a biodegradable poly (lactide-co-glycolide) (PLGA) and β-tricalcium phosphate (β-TCP) biomaterial scaffold (PT/CuB) Using 3D low-temperature rapid prototyping (LT-RP) technology.