[Safety and efficacy of ultrasound hyperthermia combined with chemotherapy and radical operation for advanced oral squamous cell carcinoma].

Purpose: To explore the safety and efficacy of ultrasound hyperthermia combined with chemotherapy and radical operation for advanced oral squamous cell carcinoma (OSCC).

Methods: Nine patients who had definite pathological diagnosis were enrolled in this clinical trail from 2015 to 2016. All patients underwent ultrasound hyperthermia combined with chemotherapy before radical operation.

[The radiosensitization of nimotuzumab on CAL-27 cells after I seeds irradiation].

Purpose: To observe the inhibitory effect of nimotuzumab combined with low-dose continuous irradiation using I seeds on CAL-27 cells originating from human tongue squamous carcinoma, and explore the radiosensitization of nimotuzumab on human tongue squamous carcinoma CAL-27 irradiated with I seeds.

Methods: The exponential-phase CAL-27 cells were randomly divided into 4 groups: control group, I seeds irradiation group, nimotuzumab group, nimotuzumab plus I seeds irradiation group. CCK-8 assay was used to detect the inhibitory effect of I seeds irradiation on CAL-27 cancer cells, and flow cytometry assays were performed to calculate the apoptosis rate of cells and cell cycle from each group.