Objective: To evaluate the influence of environmental lead exposure on infant's blood lead through integrated exposure uptake biokinetic model for lead in children (IEUBK) model, based on environmental lead and prenatal lead exposure.
Methods: The data is from a prospective study conducted among pregnant women during 2005 -2007. Blood lead of the pregnant women in the late pregnancy, environmental lead values including lead concentration in soil, air and drink-water were measured.
Objective: To identify the prevalence of depression symptoms among employees in Shanghai and to explore the association of job stress factors with depression symptoms.
Methods: Seven kinds of occupations were selected as subjects by convenient cluster sampling. Job stresses were assessed by core job stress scale and depression symptoms were measured by epidemiological survey depression scale (CES-D).
The association of lead toxicity with delta -aminolevulinic acid dehydratase (ALAD) and vitamin D receptor gene polymorphisms was examined in 216 workers occupationally exposed to lead. Urinary N-acetyl- beta-glucosaminidase (UNAG) activity and albumin concentration, adjusted by creatinine, were measured as biomarkers of nephrotoxicity. Genotyping was performed using polymerase chain reaction and restricted fragment length polymorphisms.
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