First measurement of W boson production in association with a single Charm quark in pp collisions at sqrt(s)=1.96 TeV.

We present the first measurement of the production cross section of a W boson with a single charm quark (c) in pp collisions at sqrt(s)=1.96 TeV, using soft muon tagging of c jets. In a data sample of approximately 1.

Observation of orbitally excited B(s) mesons.

We report the observation of two narrow resonances consistent with states of orbitally excited (L=1) B_(s) mesons using 1 fb;(-1) of pp[over ] collisions at sqrt[s]=1.96 TeV collected with the Collider Detector at Fermilab II detector at the Fermilab Tevatron. We use two-body decays into K- and B+ mesons reconstructed as B(+)-->J/psiK(+), J/psi-->mu(+)mu(-) or B(+)-->D[over ](0)pi(+), D[over ](0)-->K(+)pi(-).

Direct measurement of the W Boson width in ppover collisions at square roots = 1.96 TeV.

A direct measurement of the total decay width of the W boson Gamma(W) is presented using 350 pb(-1) of data from pp[over ] collisions at square root s = 1.96 TeV collected with the CDF II detector at the Fermilab Tevatron. The width is determined by normalizing predicted signal and background distributions to 230 185 W candidates decaying to enu and micronu in the transverse-mass region 50 View Article and Find Full Text PDF

Cross-section-constrained top-quark mass measurement from dilepton events at the Tevatron.

We report the first top-quark mass measurement that uses a cross-section constraint to improve the mass determination. This measurement is made with a dilepton tt event candidate sample collected with the Collider Detector II at Fermilab. From a data sample corresponding to an integrated luminosity of 1.

Search for standard model Higgs bosons produced in association with W bosons.

We report on the results of a search for standard model Higgs bosons produced in association with W bosons from pp[over] collisions at sqrt[s]=1.96 TeV. The search uses a data sample corresponding to approximately 1 fb(-1) of integrated luminosity.

Measurement of inclusive jet cross sections in Z/gamma*(-->e+e-) + jets production in pp[over ] collisions at square root s = 1.96 TeV.

Inclusive jet cross sections in Z/gamma* events, with Z/gamma* decaying into an electron-positron pair, are measured as a function of jet transverse momentum and jet multiplicity in pp[over ] collisions at square root s = 1.96 TeV with the upgraded Collider Detector at Fermilab in run II, based on an integrated luminosity of 1.7 fb(-1).

Search for Bs0 --> micro+ micro- and B0 --> micro+ micro- decays with 2 fb-1 of pp collisions.

We have performed a search for B(s)(0) --> micro(+) micro(-) and B(0) --> micro(+) micro(-) decays in pp collisions at square root s = 1.96 TeV using 2 fb(-1) of integrated luminosity collected by the CDF II detector at the Fermilab Tevatron Collider. The observed number of B(s)(0) and B0 candidates is consistent with background expectations.

Photodynamic therapy of cancer. Basic principles and applications.

Photodynamic therapy (PDT) is a minimally invasive therapeutic modality approved for clinical treatment of several types of cancer and non-oncological disorders. In PDT, a compound with photosensitising properties (photosensitiser, PS) is selectively accumulated in malignant tissues. The subsequent activation of the PS by visible light, preferentially in the red region of the visible spectrum (lambda>or=600 nm), where tissues are more permeable to light, generates reactive oxygen species, mainly singlet oxygen ((1)O(2)), responsible for cytotoxicity of neoplastic cells and tumour regression.

[Mohs micrographic surgery: aplication of this technique to penile neoplasms].

Mohs micrographic surgery is a surgical technique that allows the excision in successive layers of cutaneous malignancies with the higher cure rates. At the same time, this surgical technique offers the maximal preservation of normal tissue. That is possible because Mohs surgery provides the advantage of microscopically controlled tumor-free borders in each stage guiding the surgeon in the tumor persistence until the complete surgical excision.

Genetic variability in hepatitis C virus and its role in antiviral treatment response.

Hepatitis C virus (HCV) is a major health problem worldwide, infecting an estimated 170 million people. The high genetic variability of HCV contributes to the chronicity of hepatitis C. Here, we report results from a large-scale sequence analysis of 67 patients infected with HCV genotype 1, 23 with subtype 1a and 44 with subtype 1b.

Search for exclusive gammagamma production in Hadron-Hadron collisions.

We have searched for exclusive gammagamma production in proton-antiproton collisions at sqrt[s]=1.96 TeV, using 532 pb(-1) of integrated luminosity taken by the run II Collider Detector at Fermilab. The event signature requires two electromagnetic showers, each with transverse energy E(T)>5 GeV and pseudorapidity |eta|<1.

Magnetic interference patterns and vortices in diffusive SNS junctions.

We study theoretically the electronic and transport properties of a diffusive superconductor-normal metal-superconductor junction in the presence of a perpendicular magnetic field. We show that the field dependence of the critical current crosses over from the well-known Fraunhofer pattern in wide junctions to a monotonic decay when the width of the normal wire is smaller than the magnetic length xi(H)=square root Phi(0)/H, where H is the magnetic field and Phi(0) the flux quantum. We demonstrate that this behavior is a direct consequence of the magnetic vortex structure appearing in the normal region and predict how this structure is manifested in the local density of states.

Observation of the Heavy Baryons Sigma b and Sigma b*.

We report an observation of new bottom baryons produced in pp collisions at the Tevatron. Using 1.1 fb(-1) of data collected by the CDF II detector, we observe four Lambda b 0 pi+/- resonances in the fully reconstructed decay mode Lambda b 0-->Lambda c + pi-, where Lambda c+-->pK* pi+.

Search for chargino-neutralino production in pp collisions at sq rt[s] = 1.96 TeV.

We present a search for associated production of the chargino and neutralino supersymmetric particles using up to 1.1 fb{-1} of integrated luminosity collected by the CDF II experiment at the Tevatron pp collider at sq rt[s]=1.96 TeV.

First observation of the decay Bs0-->Ds-Ds+ and measurement of its branching ratio.

We report the observation of the exclusive decay Bs0-->Ds-Ds+ at the 7.5 standard deviation level using 355 pb(-1) of data collected by the CDF II detector in pp collisions at sqrt[s]=1.96 TeV at the Fermilab Tevatron.

Hepatitis C virus and the controversial role of the interferon sensitivity determining region in the response to interferon treatment.

The degree of variability of the interferon sensitivity determining region (ISDR) in the hepatitis C virus (HCV) genome has been postulated to predict the response to interferon therapy, mainly in patients infected with subtype 1b, although this prediction has been the subject of a long controversy. This prediction has been tested by analyzing a cohort of 67 Spanish patients infected with HCV genotype 1, 23 of which were infected with subtype 1a and 44 with subtype 1b. A sample previous to therapy with alpha-interferon plus ribavirin was obtained and several clones (between 25 and 96) including the ISDR were sequenced from each patient.

Synthesis and evaluation of N-methyl and S-methyl 11C-labeled 6-methylthio-2-(4'-N,N-dimethylamino)phenylimidazo[1,2-a]pyridines as radioligands for imaging beta-amyloid plaques in Alzheimer's disease.

6-Thiolato-substituted 2-(4'- N,N-dimethylamino)phenylimidazo[1,2- a]pyridines ( RS-IMPYs; 1- 4) were synthesized as candidates for labeling with carbon-11 ( t 1/2 = 20.4 min) and imaging of A beta plaques in living human brain using positron emission tomography (PET). K i values for binding of these ligands to Alzheimer's disease brain homogenates were measured in vitro against tritium-labeled 6 (Pittsburgh compound B).

Using evolutionary tools to refine the new hypervariable region 3 within the envelope 2 protein of hepatitis C virus.

The envelope 2 protein of hepatitis C virus (HCV) presents three hypervariable regions, named HVR1, HVR2 and HVR3, in which the presence of antigenic sites has been described. Genetic variability in these regions may reflect the generation of escape mutants as a consequence of the immune response. Therefore, these regions would tend to accumulate amino acid changes along the infection process, an effect that could be accelerated by antiviral treatments.

Comparison of neuron-like cells derived from bone marrow stem cells to those differentiated from adult brain neural stem cells.

Bone marrow-derived stem/progenitor cells have been shown by independent investigators to give rise to neural-like cells (neurons and glia) both in vitro and in vivo. The objective of the present study was to determine whether nestin-enriched cells derived from bone marrow can differentiate into cells with the same morphological and functional characteristics as neurons derived from adult brain neurogenic zones. Cell culture methods were used for generation of adult bone marrow and brain stem/progenitor cells and for studying their differentiation into neural-like cells.

Precise measurement of the top-quark mass in the lepton+jets topology at CDF II.

We present a measurement of the mass of the top quark from proton-antiproton collisions recorded at the CDF experiment in Run II of the Fermilab Tevatron. We analyze events from the single lepton plus jets final state (tt-->W(+)bW(-)b-->lnubqq'b). The top-quark mass is extracted using a direct calculation of the probability density that each event corresponds to the tt final state.

Search for new physics in high-mass electron-positron events in pp[over] collisions at square root s = 1.96 TeV.

We report the results of a search for a narrow resonance in electron-positron events in the invariant mass range of 150-950 GeV/c(2) using 1.3 fb(-1) of pp[over] collision data at square root s = 1.96 TeV collected by the CDF II detector at Fermilab.

Search for high-mass diphoton states and limits on Randall-Sundrum gravitons at CDF.

We have performed a search for new particles which decay to two photons using 1.2 fb(-1) of integrated luminosity from pp[over] collisions at square root s = 1.96 TeV collected using the CDF II detector at the Fermilab Tevatron.

First measurement of the W-boson mass in run II of the Tevatron.

We present a measurement of the W-boson mass using 200 pb{-1} of data collected in pp[over ] collisions at sqrt[s]=1.96 TeV by the CDF II detector at run II of the Fermilab Tevatron. With a sample of 63 964 W-->enu candidates and 51 128 W-->munu candidates, we measure M_{W}=80 413+/-34{stat}+/-34{syst}=80,413+/-48 MeV/c;{2}.

Two-dimensional discrete solitons in rotating lattices.

We introduce a two-dimensional discrete nonlinear Schrödinger (DNLS) equation with self-attractive cubic nonlinearity in a rotating reference frame. The model applies to a Bose-Einstein condensate stirred by a rotating strong optical lattice, or light propagation in a twisted bundle of nonlinear fibers. Two types of localized states are constructed: off-axis fundamental solitons (FSs), placed at distance R from the rotation pivot, and on-axis (R=0) vortex solitons (VSs), with vorticities S=1 and 2 .

Crossover from Josephson to multiple Andreev reflection currents in atomic contacts.

The basic current-carrying mechanism through a superconducting weak link embedded in a resistive environment undergoes a continuous crossover, as the voltage increases, from Josephson Cooper pair transfer exciting electromagnetic modes in the environment to multiple Andreev reflections leading to the creation of quasiparticles. We corroborate these ideas through measurements of the dc current-voltage characteristics of superconducting atomic contacts containing channels of arbitrary and adjustable transmission. We present a simple model, in the spirit of the classical resistively shunted junction model, that accounts well for the observed characteristics.