Is It Possible to Regenerate the Underactive Detrusor? Part 1 Molecular and Stem Cell Therapies Targeting the Urinary Bladder and Neural Axis ICI-RS 2024.

Introduction: Detrusor muscle weakness is commonly noted on urodynamics in patients with refractory voiding difficulty. No approved therapies have been proven to augment the strength of a detrusor voiding contraction.

Methods: This subject was discussed by a think-tank at the International Consultation on Incontinence- Research Society (ICI-RS) meeting held in Bristol, June 2024.

Nutritional Strategies for Optimizing Health, Sports Performance, and Recovery for Female Athletes and Other Physically Active Women: A Systematic Review.

Context: Despite the progress toward gender equality in events like the Olympic Games and other institutionalized competitions, and the rising number of women engaging in physical exercise programs, scientific studies focused on establishing specific nutritional recommendations for female athletes and other physically active women are scarce.

Objective: This systematic review aimed to compile the scientific evidence available for addressing the question "What dietary strategies, including dietary and supplementation approaches, can improve sports performance, recovery, and health status in female athletes and other physically active women?"

Data Sources: The Pubmed, Web of Science, and Scopus databases were searched.

Data Extraction: The review process involved a comprehensive search strategy using keywords connected by Boolean connectors.

The role of specialist nurses in detecting spasticity and related symptoms in multiple sclerosis.

Background: Spasticity is a frequent symptom of multiple sclerosis (MS), which may negatively influence daily living activities (ADL).

Objectives: To (1) explore the feasibility to conduct a structured interview by specialist nurses about limitations in ADL; (2) determine the percentage of people with MS (PwMS) with limitations in ADL related to spasticity; (3) to assess the knowledge about spasticity and describe its clinical features.

Design: Observational, cross-sectional, multicentre study in 16 MS units of Catalonia (Spain).

: a visual approach to explore movement trajectories.

Social networks are a dominant data source for sharing, participation, and exchanging information. For example, Twitter is a microblogging site that enables users to express opinions by transmitting brief messages (i.e.

Oncological Care During First Peruvian National Emergency COVID-19 Pandemic: A Multicentric Descriptive Study.

Purpose: The aim of this study is to evaluate the oncological care during the first state of national emergency due to the COVID-19 pandemic in several public cancer hospitals in Peru.

Materials And Methods: A multicentric cross-sectional descriptive study was conducted by interviewing adult cancer patients diagnosed and treated between January 2019 and February 2020 from 18 hospitals. This study was carried out in September 2020, the last month of the first state of national emergency.

Race/Ethnicity Differences in COVID-19 Vaccine Uptake Among Nurses.

Introduction: There is evidence for relatively lower COVID-19 vaccine uptake among people of color in the United States. The purpose of this study was to investigate associations between race/ethnicity and COVID-19 vaccine uptake among nurses.

Methods: Nurses in Southern California ( = 1183) completed a one-time, web-based survey to assess COVID-19 vaccine perceptions and uptake.

Controlling the flow balance: In vitro characterization of a pulsatile total artificial heart in preload and afterload sensitivity.

The objective of this study is to identify the preload and afterload sensitivity of the ReinHeart TAH 2.0. For adequate left-right flow balance, the concept of a reduced right stroke volume (by about 10%) and active adaption of the right diastole duration are evaluated concerning the controllability of the flow balance.

VERTIGo: A Visual Platform for Querying and Exploring Large Multilayer Networks.

Many real world data can be modeled by a graph with a set of nodes interconnected to each other by multiple relationships. Such a rich graph is called multilayer graph or network. Providing useful visualization tools to support the query process for such graphs is challenging.

Acceptability and Feasibility of Callascope Self-Imaging of the Cervix among Women in Ventanilla, Peru: A Mixed Methods Pilot Study.

Background: Barriers that prevent adherence to cervical cancer screening programs in low-income communities include, among others, fear of and discomfort associated with the speculum during pelvic exams and difficulties in accessing health facilities. To address these barriers, a low-cost medical device, the Callascope was developed for self-imaging of the cervix. The device has a 2 MP camera connected to a smartphone and a disposable inserter with an asymmetrical tip to replace the speculum.

Experimental investigation of right-left flow balance concepts for a total artificial heart.

A total artificial heart (TAH) must be designed to autonomously balance the flows of the systemic and pulmonary circulation to prevent potentially lethal lung damage. The flow difference between the systemic and pulmonary circulation is mainly caused by the bronchial (arteries) shunt flow and can change dynamically. The ReinHeart TAH consists of only one actuator that ejects blood alternately from the right and left pump chamber.

Redescription and DNA barcoding of diurnal moth Athroolopha latimargoRothschild, 1914 bona sp., stat. rev. from the southern Iberian Peninsula (Lepidoptera: Geometridae: Ennominae).

The rare and diurnal geometrid moth Athroolopha latimargo Rothschild, 1914 bona sp., stat. rev.

miR-146a rs2431697 identifies myeloproliferative neoplasm patients with higher secondary myelofibrosis progression risk.

Myelofibrosis (MF) occurs as part of the natural history of polycythemia vera (PV) and essential thrombocythemia (ET), and remarkably shortens survival. Although JAK2V617F and CALR allele burden are the main transformation risk factors, inflammation plays a critical role by driving clonal expansion toward end-stage disease. NF-κB is a key mediator of inflammation-induced carcinogenesis.

An Integrative Review of Nurse-to-Nurse Incivility, Hostility, and Workplace Violence: A GPS for Nurse Leaders.

Bullying, lateral violence, and incivility are real phenomena in the nursing workplace and remain widespread across all care settings. The American Nurses Association recommends zero tolerance for any form of violence from any source and adopting evidence-based strategies to mitigate incivility and bullying. This integrative review examined the evidence regarding nurse-to-nurse incivility, bullying, and workplace violence for 4 nurse populations-student, new graduate, experienced, and academic faculty.

Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes.

Background: Beetroot juice (BJ) is classified as a high-level supplement for improving sports performance. There is some controversy over the benefits of BJ supplementation for endurance exercise performance, especially when referring to well-trained athletes. This study examines the effects of acute BJ supplementation on cardioventilatory responses, exercise economy/efficiency, slow component of oxygen uptake, time trial performance, blood lactate, energy consumption, and carbohydrate and fat oxidation.

Effects of Beetroot Juice Supplementation on Performance and Fatigue in a 30-s All-Out Sprint Exercise: A Randomized, Double-Blind Cross-Over Study.

As a nitric oxide precursor, beetroot juice (BJ) is known to enhance high-intensity exercise performance (80⁻100% VO) yet its impacts on higher intensity sprint exercise (>100% VO) remain to be established. This study sought to examine the effects of BJ supplementation on performance and subsequent fatigue during an all-out sprint exercise. Using a randomized cross-over, double-blind, placebo-controlled design, 15 healthy resistance-trained men (22.

MultiStream: A Multiresolution Streamgraph Approach to Explore Hierarchical Time Series.

Multiple time series are a set of multiple quantitative variables occurring at the same interval. They are present in many domains such as medicine, finance, and manufacturing for analytical purposes. In recent years, streamgraph visualization (evolved from ThemeRiver) has been widely used for representing temporal evolution patterns in multiple time series.

Nutritional needs in the professional practice of swimming: a review.

Purpose: Swimming requires developing a high aerobic and anaerobic capacity for strength and technical efficiency. The purpose of this study was to establish the nutritional requirements and dietary strategies that can optimize swimming performance.

Methods: Several related studies retrieved from the databases, Dialnet, Elsevier, Medline, Pubmed, and Web of Science, through keyword search strategies were reviewed.

Effects of beetroot juice supplementation on intermittent high-intensity exercise efforts.

Beetroot juice contains high levels of inorganic nitrate (NO) and its intake has proved effective at increasing blood nitric oxide (NO) concentrations. Given the effects of NO in promoting vasodilation and blood flow with beneficial impacts on muscle contraction, several studies have detected an ergogenic effect of beetroot juice supplementation on exercise efforts with high oxidative energy metabolism demands. However, only a scarce yet growing number of investigations have sought to assess the effects of this supplement on performance at high-intensity exercise.

Effects of Beetroot Juice Supplementation on a 30-s High-Intensity Inertial Cycle Ergometer Test.

Beetroot juice (BJ) is rich in inorganic nitrates and has proved effective at increasing blood nitric oxide (NO) levels. When used as a supplement BJ has shown an ergogenic effect on cardiorespiratory resistance exercise modalities, yet few studies have examined its impact on high intensity efforts. To assess the effects of BJ intake on anaerobic performance in a Wingate test.

Effect of surfactant concentration on the responsiveness of a thermoresponsive copolymer/surfactant mixture with potential application on "Smart" foams formulations.

Hypothesis: Previous efforts to formulate smart foams composed of mixtures of PNIPAAm, a thermoresponsive uncharged polymer, and surfactants have failed because the surfactant displaces the PNIPAAm from the liquid-air interface, removing the thermal responsiveness. We hypothesized that thermoresponsive foams could be formulated with such a mixture if a charged surfactant were used in order to anchor an oppositely charged brush-type polyelectrolyte, for which PNIPAAm could be incorporated as side chains, to the interface.

Experiments: A brush-type negatively charged co-polyelectrolyte (Cop-L) with PNIPAAm as side chains was synthetized.

Effects of Beetroot Juice Supplementation on Cardiorespiratory Endurance in Athletes. A Systematic Review.

Athletes use nutritional supplementation to enhance the effects of training and achieve improvements in their athletic performance. Beetroot juice increases levels of nitric oxide (NO), which serves multiple functions related to increased blood flow, gas exchange, mitochondrial biogenesis and efficiency, and strengthening of muscle contraction. These biomarker improvements indicate that supplementation with beetroot juice could have ergogenic effects on cardiorespiratory endurance that would benefit athletic performance.

An Integrative Review of Pain Resource Nurse Programs.

Mismanaged pain challenges health care systems. In the early 1990s, pain resource nurse programs were developed by Ferrell and colleagues. Variations of the model have existed for more than 20 years.

Urinary Continence Following Repair of Intermediate and High Urogenital Sinus (UGS) in CAH. Experience with 55 Cases.

Aim: To evaluate postoperative urinary continence in patients with congenital adrenal hyperplasia (CAH) with intermediate (IT) and high urogenital sinus (UGS) who underwent a UGS mobilization maneuver.

Methods: We called IT to those that although needing an aggressive dissection to get to the vagina, still have enough urethra proximal to the vaginal confluence. Very low variants are excluded from this analysis.