Voices and experiences of Moroccan-heritage women and men in Spain: Understanding affective reactions to injustice through mixed-methods.

Objective: Research has not often delved into the experiences of the Moroccan-heritage community in Western societies. We followed a mixed-methods approach, combining qualitative with quantitative methods, applying an intersectionality perspective to analyze the feelings and perceptions of Moroccan-heritage people about their situation in Spain, interaction with Spaniards, perceived discrimination, and metaperceptions to understand their affective reactions to injustice (Studies 1 and 2), and willingness to mobilize (Study 2).

Method: In Study 1, we conducted four discussion groups with Moroccan-heritage women ( = 12) and men ( = 13) separately.

A convergent growth approach to electroactive ferrocene rich carbosilane- and siloxane-based dendrons, dendrimers, and dendronized polymers.

The construction of the first members of a novel family of structurally well-defined, ferrocenyl rich, dendritic macromolecules based on carbosilane skeletons and siloxane linkages has been achieved a convergent growth approach. Starting from triferrocenylvinylsilane FcSiCHCH (1) (Fc = Fe(η-CH)(η-CH) as the key monomer, the sequential utilization of platinum-catalyzed hydrosilylation and alkenylation steps with Grignard reagents (allylmagnesium bromide) can be applied to prepare three different branched structures: multiferrocenyl-terminated dendrons 2 and 3, dendrimers 4 and 5, and dendronized polymers 7n-9n. All of the dendritic metallomacromolecules have been thoroughly characterized using a combination of elemental analysis, multinuclear (H, C, Si) NMR spectroscopy, FT-IR and MALDI-TOF mass spectrometry, to establish their chemical structures and properties.

Synthesis of Quinoline and Dihydroquinoline Embelin Derivatives as Cardioprotective Agents.

A set of new dihydroquinoline embelin derivatives was obtained from the reaction of the natural benzoquinone embelin () with anilines and aromatic aldehydes in the presence of AgOTf. The synthesis of these compounds involves the formation of a Knoevenagel adduct, followed by nucleophilic addition of aniline and subsequent electrocyclic ring closure. The scope of the reaction regarding the aldehydes and anilines was determined.

Phenolic and quinone methide nor-triterpenes as selective NLRP3 inflammasome inhibitors.

Dysregulated inflammasome activity, particularly of the NLRP3 inflammasome, is associated with the development of several inflammatory diseases. The study of molecules directly targeting NLRP3 is an emerging field in the discovery of new therapeutic compounds for the treatment of inflammatory disorders. Friedelane triterpenes are biologically active phytochemicals having a wide range of activities including anti-inflammatory effects.

Labdane conjugates protect cardiomyocytes from doxorubicin-induced cardiotoxicity.

The cardiovascular side effects associated with doxorubicin (DOX), a wide spectrum anticancer drug, have limited its clinical application. Therefore, to explore novel strategies with cardioprotective effects, a series of new labdane conjugates were prepared (6a-6c and 8a-8d) from the natural diterpene labdanodiol (1). These hybrid compounds contain anti-inflammatory privileged structures such as naphthalimide, naphthoquinone, and furanonaphthoquinone.

Thiol-yne chemistry of diferrocenylacetylene: from synthesis and electrochemistry to theoretical studies.

The thiol-yne coupling chemistry of diferrocenylacetylene (FcCCFc) 1, bearing two electron rich and redox-active ferrocenyl units (Fc = Fe(η-CH)(η-CH)) and an internal triple bond, has been investigated for the first time. In order to determine whether steric limitations might affect hydrothiolation, a model reaction using a functionalized monothiol was tested, namely 2-mercaptoethanol I. The thiol-diferrocenylacetylene reactions were initiated either thermally (in toluene with AIBN) or by UV light irradiation (in THF and in the presence of DMPA as the photoinitiator).

Evolution of Type D Personality Traits After Cochlear Implantation in Severely Hearing Impaired Adults 55 Years and Older: An Exploratory Prospective, Longitudinal, Controlled, Multicenter Study.

Purpose: To study the evolution of type D personality traits in older adults after cochlear implantation compared with a control group of severely hearing impaired older adults who did not receive a cochlear implant (CI). The influence of COVID-19 on this evolution was also explored. Type D personality combines a high degree of negative affectivity (NA) and social inhibition (SI).

Dehydroisohispanolone as a Promising NLRP3 Inhibitor Agent: Bioevaluation and Molecular Docking.

Dehydroisohispanolone (DIH), is a labdane diterpene that has exhibited anti-inflammatory activity via inhibition of NF-κB activation, although its potential effects on inflammasome activation remain unexplored. This study aims to elucidate whether DIH modulates NLR family pyrin domain-containing protein 3 (NLRP3) inflammasome in macrophages. Our findings show that DIH inhibited NLRP3 activation triggered by Nigericin (Nig), adenosine triphosphate (ATP) and monosodium urate (MSU) crystals, indicating broad inhibitory effects.

Active and Passive Facilitation Tendencies at Work Towards Sexy and Professional Women: The Role of Stereotypes and Emotions.

Stereotypes have important social consequences, such as promoting female discrimination in the workplace, which depends on how women are categorized. Extending prior work, here we analyze how two important female subgroups, women who are categorized as professional or sexy women, are evaluated on key dimensions of stereotype content (morality, sociability, and competence), positive and negative emotions, and facilitation behavioral tendencies (active and passive). To this end, we adapted a previous scale of facilitation tendencies to the working environment.

Unpacking negative attitudes towards Moroccans: The interactive effect of ethnicity and gender on perceived morality.

Research on stereotyping has mainly focused on single social categories such as ethnicity or gender. Extending prior work, here we analyse the effects of the intersection of ethnicity and gender on stereotyping considering the descriptive and prescriptive components of positive and negative stereotype dimensions of morality, sociability and competence. We also examine these interaction effects on the stereotypes-emotions-facilitation behavioural tendencies link.

Awareness of the Psychological Bias of Naïve Realism Can Increase Acceptance of Cultural Differences.

Acceptance of cultural differences can contribute to diversity. However, naïve realism-the conviction that one's views are objective whereas others' are biased-might hinder intercultural coexistence. We tested, in three experimental studies, whether a cognitive strategy based on raising awareness of the naïve realism, without any reference to culture and free of emotional involvement, can have a beneficial effect on cultural acceptance.

Trust predicts COVID-19 prescribed and discretionary behavioral intentions in 23 countries.

The worldwide spread of a new coronavirus (SARS-CoV-2) since December 2019 has posed a severe threat to individuals' well-being. While the world at large is waiting that the released vaccines immunize most citizens, public health experts suggest that, in the meantime, it is only through behavior change that the spread of COVID-19 can be controlled. Importantly, the required behaviors are aimed not only at safeguarding one's own health.

The Way We See Others in Intercultural Relations: The Role of Stereotypes in the Acculturation Preferences of Spanish and Moroccan-Origin Adolescents.

Although the relationship between stereotypes and acculturation preferences has been previously studied from the majority perspective among adults, the perspective of adolescents and minority groups is understudied. This research analyzed the contribution of four stereotype dimensions (i.e.

Multicentre Spanish study found no incidences of viral transmission in infants born to mothers with COVID-19.

Aim: Our aim was to describe the clinical features of mothers infected with COVID-19 and examine any potential vertical mother to newborn transmission. We also assessed how effective the discharge recommendations were in preventing transmission during the first month of life.

Methods: This multicentre descriptive study involved 16 Spanish hospitals.

Dehydrohispanolone Derivatives Attenuate the Inflammatory Response through the Modulation of Inflammasome Activation.

The NLRP3 inflammasome plays a critical role in inflammation-mediated human diseases and represents a promising drug target for novel anti-inflammatory therapies. Hispanolone is a labdane diterpenoid isolated from the aerial parts of species. This diterpenoid and some derivatives have demonstrated anti-inflammatory effects in classical inflammatory pathways.

Bisphenol A induces coronary endothelial cell necroptosis by activating RIP3/CamKII dependent pathway.

Epidemiological studies link long term exposure to xenoestrogen Bisphenol-A to adverse cardiovascular effects. Our previous results show that BPA induces hypertension by a mechanism involving CamKII activation and increased redox stress caused by eNOS uncoupling. Recently, CamKII sustained activation has been recognized as a central mediator of programmed cell death in cardiovascular diseases, including necroptosis.

Current status of terpenoids as inflammasome inhibitors.

Increasing evidence supports NLRP3 inflammasome as a new target to control inflammation. Dysregulation of NLRP3 inflammasome has been reported to be involved in the pathogenesis of several human inflammatory diseases. However, no NLRP3 inflammasome inhibitors are available in clinic.

Exploring clinical, echocardiographic and molecular biomarkers to predict bronchopulmonary dysplasia.

Introduction: Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease in childhood, related to prematurity, and the most common cause of pulmonary hypertension (PH) secondary to pulmonary disease in children. Moderate and severe BPD have a worse outcome and relate more frequently with PH. The prediction of moderate or severe BPD development in extremely premature newborns is vital to implement preventive strategies.

Semisynthesis and Inhibitory Effects of Solidagenone Derivatives on TLR-Mediated Inflammatory Responses.

A series of nine derivatives (⁻) were prepared from the diterpene solidagenone () and their structures were elucidated by means of spectroscopic studies. Their ability to inhibit inflammatory responses elicited in peritoneal macrophages by TLR ligands was investigated. Compounds and showed significant anti-inflammatory effects, as they inhibited the protein expression of nitric oxide synthase (NOS-2), cyclooxygenase-2 (COX-2), and cytokine production (TNF-α, IL-6, and IL-12) induced by the ligand of TLR4, lipopolysaccharide (LPS), acting at the transcriptional level.

Titanium thiosalicylate complexes: functional metalloligands for the construction of redox-active heterometallic architectures.

The titanium complex [TiCp*(thiosal)(thiosalH)] (1) has been synthesised by reaction of [TiCp*Me], Cp* = η-CMe, with thiosalicylic acid (Hthiosal). Complex 1 reacts with [M(μ-OH)(COD)] (M = Rh, Ir) to yield the corresponding early-late heterobimetallic complexes [TiCp*(thiosal)M(COD)] (M = Rh (2); Ir (3)). Carbon monoxide replaces the COD ligand in 2 and 3 leading to the respective dicarbonyl complexes [TiCp*(thiosal)M(CO)] (M = Rh (4); Ir (5)).

The Effects of Occupational Status and Sex-Typed Jobs on the Evaluation of Men and Women.

Occupational segregation by gender is one of the major problems faced by professional women in the labor market. Since the sixties, psychological explanations point out that gender stereotypes are responsible for this persistent inequality in the workforce. Nevertheless, most of research has overlooked that emotions are particularly important as the discrimination faced by professional women is better explained by the ambivalent feelings they provoke than by stereotyping.

Synergistic effect of MoS and diamond nanoparticles in electrochemical sensors: determination of the anticonvulsant drug valproic acid.

The authors describe an electrochemical sensor based on the use of diamond nanoparticles (DNPs) and molybdenum disulfide (MoS) platelets. The sensor was applied to the voltammetric determination of the anticonvulsant valproic acid which was previously derivatized with ferrocene. The MoS platelets were obtained by an exfoliation method, and the DNPs were directly dispersed in water and subsequently deposited on a glassy carbon electrode (GCE).

Adjustment Outcomes of Native and Immigrant Youth in Spain: A Mediation Model.

This work proposes a conceptual model of psychological adjustment of native and immigrant adolescents who live in Spain. Psychological adjustment was expected to mediate between perceived family support and adolescents' school adjustment and problem behaviors. Spanish adolescents (n = 156) and immigrant adolescents (n = 137) filled out a self-report questionnaire regarding their perceived family support, psychological adjustment (i.

Extracting the Evaluations of Stereotypes: Bi-factor Model of the Stereotype Content Structure.

Stereotype dimensions-competence, morality and sociability-are fundamental to studying the perception of other groups. These dimensions have shown moderate/high positive correlations with each other that do not reflect the theoretical expectations. The explanation for this (e.

Formation of unexpected silicon- and disiloxane-bridged multiferrocenyl derivatives bearing Si-O-CH[double bond, length as m-dash]CH and Si-(CH)C(CH) substituents via cleavage of tetrahydrofuran and trapping of its ring fragments.

The formation of a family of silicon- and siloxane-bridged multiferrocenyl derivatives carrying different functional groups attached to silicon, including Fc(CH)C(CH)SiCH[double bond, length as m-dash]CH (5), Fc(CH[double bond, length as m-dash]CH-O)SiCH[double bond, length as m-dash]CH (6), Fc(OH)SiCH[double bond, length as m-dash]CH (7), Fc(CH[double bond, length as m-dash]CH-O)Si-O-Si(O-CH[double bond, length as m-dash]CH)Fc (8) and Fc(CH[double bond, length as m-dash]CH-O)Si-O-SiFc (9) is described. Silyl vinyl ether molecules 6, 8 and 9 and the heteroleptic vinylsilane 5 resulted from the competing metathesis reaction of lithioferrocene (FcLi), CH[double bond, length as m-dash]CH-OLi or (CH)C(CH)Li with the corresponding multifunctional chlorosilane, ClSiCH[double bond, length as m-dash]CH or ClSi-O-SiCl. The last two organolithium species have been likely formed in situ by fragmentation of the tetrahydrofuran solvent.