[Indications and perioperative results of completion pneumonectomy].

Completion pneumonectomy (CP) means the removal of the entire residual lung tissue after previously performed lung resection. Mortality and morbidity of CP are higher when compared to those of standard pneumonectomy. In this article, we give an overview on indications and perioperative results of CP.

[Doege-Potter syndrome with giant malignant solitary fibrous tumour of the pleura].

Infrequent solitary fibrous tumours of the pleura are associated with hypoglycaemia only in a few percent of the cases; this condition is called Doege-Potter syndrome, named after its first descriptors. Our 63 years old male patient has previously undergone clinical treatment for intrathoracic fluid accumulation on the left side caused by a giant tumour-like mass in the lower left lobe detected by CT scan. In the course of further investigations performed due to increasing load-induced dyspnoea, lung core biopsy verified low grade sarcoma in the tumour.

[Not Available].

Objective: The significance of surgery in elderly patients with lung cancer is debated. The age is a predisposing risk factor for developing cancer thereby the possibilities of surgical procedure is increasing in the elderly patients. To clarify the benefit of surgery in patients with lung cancer aged 70 years and over we reviewed our cohort of 206 patients.

[Not Available].

Surgery of mostly benign giant tumours involving large part of the chest is a special surgical challenge. The problems comprise difficulties of surgical technique, management of the narcosis and postoperative intensive care. An additional peculiarity of our case is the extreme confliction of the otherwise presumably evident indication for surgery.

Unicentric mixed variant Castleman disease associated with intrabronchial plasmacytoma.

Unlabelled: Castleman disease (CD), described as a heterogeneous lymphoproliferative disorder, can be divided into different subtypes according to clinical appearance (unicentric and multicentric form) and histopathological features (hyaline vascular, plasma cell, mixed type, human herpesvirus 8-associated and multicentric not otherwise specified). Unicentric CD is known to be usually of the hyaline vascular variant, plasma cell and mixed type of this form are quite uncommon. Malignancies are mainly associated with the multicentric form.

Sarcoidosis lymphoma syndrome - the value of PET-CT in the diagnosis.

We report a 52-year-old patient who developed B-cell non-Hodgkin's lymphoma subsequent to sarcoidosis. Sarcoidosis was diagnosed 16 years ago and remained asymptomatic for 14 years after steroid treatment. She presented with new symptoms of arthralgia, photosensitivity, butterfly erythema, autoimmune antibodies (ANA, chromatin positivity) associated with progression of the known left upper lobe lesion on the chest X-ray suggesting primary autoimmune disease (systemic lupus erythematosus).

[Surgical treatment of acute descending necrotising mediastinitis].

Introduction: Acute descending necrotizing mediastinitis (DNM) is a severe septic inflammation of the mediastinum with necrosis, which progrediates rapidly and leads to death without adequate surgical treatment in 80% of cases.

Patients And Method: 17 patients were treated with acute DNM between 1999 and 2012 at the Thoracic Surgical Department of Koranyi National Institute and Semmelweis University of Hungary. The infection source was primarily in the head-neck region with dental infections in eight cases, retro/parapharyngeal abscess in four patients, primary collar phlegmone and abscess in one case and two retrotonsillar abscesses.

[Isolated bronchial resection for tumor].

Tumors that are confined to specific areas of the airway (e.g. left main stem bronchus or the bronchus intermedius) can be removed with resections of the bronchus only and preservation of the parenchyma.

[Repair for anterior chest wall deformity by Nuss procedure performed in young adults and older adolescents].

Results of 86 minimally invasive anterior chest wall reconstructions for pectus excavatum by the method of Nuss are evaluated retrospectively. Complications, possible ways of avoiding those and technical details of the operation are discussed. Nuss method is also evaluated in terms of suitability patients' age.

[Surgical aspects of the new TNM system for lung cancer].

Recent results of basic research in lung cancer and development of new antitumoral drugs provided the bases for the revision of TNM system of lung cancer. In addition, the VI-th Edition of TNM classification was based on a relatively small database anyway. Multicentric analysis and biostatistical evaluation were carried out by the initiation of IASCL.

Efficacy and safety of TachoSil® versus standard treatment of air leakage after pulmonary lobectomy.

Objectives: Alveolar air leakage remains a serious problem in lung surgery, being associated with increased postoperative morbidity, prolonged hospital stay and greater health-care costs. The aim of this study was to evaluate the sealing efficacy and safety of the surgical patch, TachoSil®, in lung surgery.

Methods: Patients undergoing elective pulmonary lobectomy who had grade 1 or 2 air leakage (evaluated by the water submersion test) after primary stapling and limited suturing were randomised at 12 European centres to open-label treatment with TachoSil® or standard surgical treatment (resuturing, stapling or no further treatment at the surgeons' discretion).

Relationship between TP53 tumour suppressor gene mutations and smoking-related bulky DNA adducts in a lung cancer study population from Hungary.

Lung cancer rate in Hungary is one of the highest in the world among men and also very high among women, for reasons not clearly understood yet. The aim of the study was to explore characteristics of DNA damage and TP53 gene mutations in lung cancer from Hungary. Tissue samples from 104 lung resections for lung cancer patients, both men and women, operated on for non-small cell lung cancer, specifically, primary squamous cell carcinoma or adenocarcinoma were studied.

[The possibility of surgery for small cell lung cancer (state of art)].

The author provides information about epidemiology as well as surgical practice for small cell lung cancer (SCLC) in Hungary. It is emphasized that, based on the author's experience and on international consensus, TNM system is the basis of accurate oncological treatment. The oncological management of SCLC is summarized, which is based on surgery.

[Covering of bronchial stump fistula with omental flap].

Previous lobectomy was performed on a 71 year old woman because of right inferior lobe lung adenocarcinoma. On the 25th postoperative day bronchial stump leak developed. During reoperation authors covered the fistula with a gastroepiploic omental flap which was pulled through an incision on the diaphragm.

[Prevention and treatment of bronchopleural fistula using pedicled muscle flaps].

Authors used pedicled muscle flaps for prevention and treatment of bronchopleural fistulas in 55 patients. Thirty five flaps were used for prevention and 21 for treatment of bronchial stump leak. After using 19 pectoral, 18 latissimus, 10 diaphragm, 3 intercostals, 2 serratus and 4 double muscle flaps, only two flap necrosis occurred due to insufficient flap perfusion.

Lung cancer and its operable brain metastasis: survival rate and staging problems.

Background: We assessed the survival rates regarding different stages of operable lung cancers causing operable brain metastasis in patients with or without cancer-related symptoms. The correlation between survival rates and the disease-free interval between lung surgery and metastasectomy was studied.

Methods: Sixty-five patients were operated on for lung cancer and brain metastases.

[Lung harvesting in Hungary--results of the first two years].

Objective: Hungarian patients undergo lung transplantation within bilateral cooperation in Vienna, Austria since 1995. Lung harvesting was introduced in 2002 in Hungary. Before 2002 Hungarian patients get 16 donor lungs from abroad, and 4 patients died while being on the waiting list for transplantation.

DNA adducts in tumour, normal peripheral lung and bronchus, and peripheral blood lymphocytes from smoking and non-smoking lung cancer patients: correlations between tissues and detection by 32P-postlabelling and immunoassay.

Smoking is a major risk factor for lung cancer. This comparative study of smoking-related carcinogen-DNA adducts in pulmonary tissues and peripheral blood lymphocytes aims to further explore the primary DNA damaging processes by cigarette smoke in target and surrogate tissues. Samples of tumour and normal peripheral lung tissue, normal bronchial tissue and peripheral blood lymphocytes were obtained from a total of 85 lung cancer patients who underwent lung resection.

Efficacy and safety of topical application of human fibrinogen/thrombin-coated collagen patch (TachoComb) for treatment of air leakage after standard lobectomy.

Objectives: Persisting air leakage after pulmonary resection remains a significant problem. The aim of the study was to evaluate the incidence of air leakage after standard lobectomy and test the efficacy and safety of TachoComb (TC).

Methods: A total of 189 patients undergoing lobectomy were enrolled in a multi-centre, open, randomised, and prospective study to test the efficacy and safety of TachoComb (TC) for air leakage treatment.

[Changes in algorythm of surgical management for non-small cell lung cancer (NSCLC)].

In Hungary the incidence of lung cancer is growing further and the proportion of patients undergoing surgery is less than 30%. Some improvement is indicated by the rate of explorations decreasing to less than 10%. On the other hand the number of adenocarcinomas has grown to take over the position of the squamous cell carcinomas among the patients operated on.

[Surgical treatment for metastatic renal cell tumors of the lung].

Unlabelled: Number of resection for lung metastasis in Hungary is low, however surgery provides benefit for patients using an integrated oncological therapeutical protocol. The authors give a retrospective analysis of 57 patients operated on for metastatic renal cell tumor to the lung. Metastases were discovered most frequently by x-ray picture of an accidental investigation or screening at symptom-free patients and in 32 cases solitary and in 25 cases multiple deposits were proved.

Late complications of coloesophagoplasty and long-term features of adaptation.

Objectives: Revisional surgery of late complications after 141 substernal by-pass operations (1962-1990), except three cases with isoperistaltic (except seven with anisoperistaltic) transverse colon grafts for caustic esophageal strictures, are presented. Long-term adaptation of the grafts was investigated with cineradiographical and histochemical methods.

Methods: Correction of the "pseudodiverticulum" of the proximal anastomosis as a complication of the standard by-pass procedure (in five patients) was achieved by closure of the esophagus below the anastomosis or by end-to-end reanastomosis.