Publications by authors named "Crowley J"

Objective: In the United Kingdom (UK) and most countries worldwide, midwives are professionally required to undertake an initial perinatal mental health (PMH) risk assessment at every maternity contact. However, studies have found that midwives feel that they are not well-equipped to provide effective care for women with PMH needs. This study explores how the newly qualified midwives (NQMs) are prepared through pre-registration midwifery education and placements to have sufficient confidence in their , , , (KASH) for their post-registration PMH role.

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Reducing emissions is vital to improve sustainability, and industry leaders have set emission goals to reduce gross emissions, lower emissions intensity, or reach net zero. However, additional traits should also be measured and compared in terms of their impact on the broader definition of sustainability. In addition to environmental impact, a sustainable breeding objective must consider profit, animal welfare, farmer well-being, and social responsibility.

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New particle formation (NPF) in the tropical upper troposphere is a globally important source of atmospheric aerosols. It is known to occur over the Amazon basin, but the nucleation mechanism and chemical precursors have yet to be identified. Here we present comprehensive in situ aircraft measurements showing that extremely low-volatile oxidation products of isoprene, particularly certain organonitrates, drive NPF in the Amazonian upper troposphere.

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  • Forgiveness is a key aspect of many religions and offers health and relationship benefits, particularly in lowering stress associated with holding onto negative feelings.
  • This study explored the relationship between forgiveness and immune response (measured by Epstein-Barr virus antibodies) while considering personal factors like relationship value and exploitation risk.
  • Results showed that forgiveness had no notable impact on immune function in low-value relationships, but significantly improved immune health in moderate to high-value relationships, highlighting the importance of the context in which forgiveness occurs.
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This update, titled Providing Quality Family Planning Services in the United States: Recommendations of the U.S. Office of Population Affairs (Revised 2024), provides recommendations developed by the Office of Population Affairs (OPA) within the Office of the Assistant Secretary for Health at the U.

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Introduction: Dentists and oral health practitioners have a potential role in supporting the prevention and management of noncommunicable diseases. However, the extent to which university education prepares practitioners to provide nutrition care is unclear. This scoping review identifies and synthesises the evidence related to university-level nutrition education provided to dental and oral health students globally.

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Current genetic research on obsessive-compulsive disorder (OCD) supports contributions to risk specifically from common single nucleotide variants (SNVs), along with rare coding SNVs and small insertion-deletions (indels). The contribution to OCD risk from rare copy number variants (CNVs), however, has not been formally assessed at a similar scale. Here we describe an analysis of rare CNVs called from genotype array data in 2248 deeply phenotyped OCD cases and 3608 unaffected controls from Sweden and Norway.

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  • ABP 654 is a biosimilar to ustekinumab, sharing identical amino acid sequences and similar safety and pharmacokinetics in healthy individuals.
  • A clinical study was conducted to compare the efficacy and safety of ABP 654 versus ustekinumab in patients with moderate-to-severe plaque psoriasis, focusing on improvements in psoriasis severity.
  • Results showed no significant difference in efficacy (PASI improvement) between ABP 654 and ustekinumab, and both treatments exhibited similar safety and immunogenicity profiles.
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Cardiac arrest in the postoperative cardiac surgery patient requires a unique set of management skills that deviates from traditional cardiopulmonary resuscitation and Advanced Cardiovascular Life Support (ACLS). Cardiac Advanced Life Support (CALS) was first proposed in 2005 to address these intricacies. The hallmark of CALS is early chest reopening and internal cardiac massage within 5 minutes of the cardiac arrest in patients unresponsive to basic life support.

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  • The study investigates the potential impact of cannulation timing (daytime vs. nighttime/weekend) on patient outcomes for venoarterial extracorporeal membrane oxygenation (VA-ECMO).
  • It was conducted as a retrospective cohort study at a large academic medical center, examining 468 patients who underwent VA-ECMO cannulation from 2011 to 2021.
  • The findings suggest that cannulating VA-ECMO at night or on weekends does not significantly affect one-year mortality rates or the need for renal replacement therapy, indicating that such procedures can be safely performed during these times.
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  • Tic disorders (TD) can significantly affect individuals and society, and understanding their genetic causes could lead to better treatments, as family history is a key risk factor.
  • A large-scale GWAS meta-analysis was conducted with nearly 10,000 TD cases and over 981,000 controls, revealing a significant genetic association, though it couldn't be replicated in another study.
  • The findings suggest a complex genetic landscape for TD, highlighting certain genes and brain regions involved, but additional research is needed to firmly establish reliable genetic links.
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  • - The study aimed to evaluate a faecal immunochemical testing (FIT) service for asymptomatic patients aged 40-75 in primary care, addressing the rising incidence of colorectal cancer in younger populations.
  • - Out of 173 patients offered FIT kits, 142 samples were analyzed; most results were normal, with 8 positive cases leading to 6 colonoscopies that found no cancer but identified polyps in half of those patients.
  • - This pilot study marks the first successful FIT service in primary care in Ireland, highlighting the need for such testing and its potential benefits in detecting colorectal health issues.
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  • The study evaluated the practices of nuclear medicine technologists in administering radiopharmaceuticals, examining various sources such as clinical observations, quality improvement projects, a survey of hospitals, and extensive IV access data.
  • Findings revealed that technologists often choose veins in flexion areas without thorough assessment and primarily rely on blind punctures, contributing to complications like extravasations.
  • The research highlighted a lack of formal protocols and training among nuclear medicine technologists, indicating a gap between their intentions and adherence to best practices in venous access.
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Intervertebral disc degeneration in dogs occurs in an accelerated way and involves calcification, which is associated with disc herniation or extrusion. The degenerative process is complex and involves the transformation of collagen fibres, loss of proteoglycans and notochord cells and a reduction in water content; however, how these processes are linked to future disc extrusion remains unknown. We have employed techniques including Fourier Transform Infra-red Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Uniaxial Compression Loading and Atomic Force Microscopy (AFM) in an attempt to gain a greater understanding of the degenerative process and its consequences on the physical properties of the disc.

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Background: Postinfectious autoimmune processes have been proposed as potential causal risk factors for obsessive-compulsive disorder (OCD). In this large population-based study, we aimed to clarify the familial coaggregation pattern between severe infections and OCD across clusters of relatives with varying degrees of relatedness.

Methods: We identified 4,916,898 individuals born in Sweden between 1960 and 2008 and followed them until the end of 2020.

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Heterobimetallic cages built from Pd and either octahedral Ru or square-planar Pt moieties and bridged by ligands with H bonding-accepting or -donating properties are reported. They showed stimulus-responsive dis- and reassembly, while guest binding was found to be dependent on the complementary properties of the guest to the host in terms of charge, size and H bonding properties.

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Metallosupramolecular architectures formed from metal ions and bridging ligands are increasing in popularity due to their range of applications and ease of self-assembly. Many are able to readily change their shape and/or function in response to an external stimulus and have the ability to encapsulate guest molecules within their internal cavities. Ferrocenyl groups (Fc) have been incorporated previously within the bridging ligands of metallosupramolecular structures due to their ideal attributes brought about by the structural and rotational flexiblity of the two cyclopentadienyl (Cp) rings coordinated to the Fe(II) centre.

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Aim: Testing the effect of Fluoride, chlorhexidine, and molecular iodine applications on the mean micro-shear bond strength (SBS) of enamel in an attempt to preserve enamel integrity during the bonding process.

Materials And Methods: The study was an observational case-control one in which 150 human teeth were classified into 10 groups according to the product kind and the prescribed treatment. Each group consisted of 15 teeth.

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Most biological membranes are curved, and both lipids and proteins play a role in generating curvature. For any given membrane shape and composition, it is not trivial to determine whether lipids are laterally distributed in a homogeneous or inhomogeneous way, and whether the inter-leaflet distribution is symmetric or not. Here we present a simple computational tool that allows to predict the preference of any lipid type for membranes with positive vs.

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Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a critical intervention for patients with severe lung failure, especially acute respiratory distress syndrome (ARDS). The weaning process from ECMO relies largely on expert opinion due to a lack of evidence-based guidelines. The ventilatory ratio (VR), which correlates with dead space and mortality in ARDS, is calculated as [minute ventilation (mL/min) x arterial pCO (mmHg)]/[predicted body weight × 100 × 37.

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The recent pandemic was caused by the emergence of a new human pathogen, SARS-CoV-2. While the rapid development of many vaccines provided an end to the immediate crisis, there remains an urgent need to understand more about this new virus and what constitutes a beneficial immune response in terms of successful resolution of infection. Indeed, this is key for development of vaccines that provide long lasting protective immunity.

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