The Risk of Developing Disabling Crohn's Disease: Validation of a Clinical Prediction Rule to Improve Treatment Decision Making.

Background: Crohn's disease (CD) is characterized by the development of complications over the course of the disease. It is crucial to identify predictive factors of disabling disease, in order to target patients for early intervention. We evaluated risk factors of disabling CD and developed a prognostic model.

EUS-guided drainage of postsurgical pelvic abscesses using lumen-apposing metal stents.

Endoscopic ultrasound (EUS) guided drainage of pelvic collections is an alternative to percutaneous or surgical drainage. We present our experience using lumen-apposing metal stents (LAMS) for the drainage of postoperative pelvic abscesses.

Online social networks and inflammatory bowel disease.

Enrolling patients for epidemiologic studies represents a challenge for researchers. Those who use traditional approaches, including in-person interviews and telephone or mail surveys, obtain increasingly lower participations. In the study by Martín-Fernández et al.

Limited effectiveness with a 10-day bismuth-containing quadruple therapy (Pylera ) in third-line recue treatment for Helicobacter pylori infection. A real-life multicenter study.

Background: Helicobacter pylori antibiotic resistance is an increasing problem worldwide. Pylera may be an option as salvage therapy.

Aim: To assess the effectiveness, safety, and tolerance of Pylera as a third-line in clinical practice.

Proton-pump inhibitors adverse effects: a review of the evidence and position statement by the Sociedad Española de Patología Digestiva.

Introduction: In the last few years a significant number of papers have related the use of proton-pump inhibitors (PPIs) to potential serious adverse effects that have resulted in social unrest.

Objective: The goal of this paper was to provide a literature review for the development of an institutional position statement by Sociedad Española de Patología Digestiva (SEPD) regarding the safety of long-term PPI use.

Material And Methods: A comprehensive review of the literature was performed to draw conclusions based on a critical assessment of the following: a) current PPI indications; b) vitamin B12 deficiency and neurological disorders; c) magnesium deficiency; d) bone fractures; e) enteric infection and pneumonia; f) interactions with thienopyridine derivatives; e) complications in cirrhotic patients.