Publications by authors named "Cristobal Dominguez"

Objectives: The aim of this study was to assess whether the use of topical pharyngeal anesthesia improves endoscopist- and patient-reported tolerance and satisfaction, the total dose of propofol used and the rate of adverse effects associated with this procedure.

Methods: This double-blind randomized clinical trial was conducted in patients undergoing elective oesophagogastroduodenoscopy, who met the inclusion criteria. Patients were randomly assigned to receive five squirts of lidocaine 10% spray (50 mg, n = 268) or placebo (n = 271) 3 min before starting the procedure or sedation.

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Aims And Objectives: To describe the outcomes of midclavicular catheters related to first insertion success rate, catheter dwell time, rate of catheter survival until the end of the treatment, and complication rates, as well as identify risk factors associated with early catheter removal.

Background: Midclavicular catheters are peripheral venous catheters that are typically 20-25 cm in length.

Design: Inception cohort study.

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Background: More than half of patients with multimorbidity require intravenous therapy during their hospital stay. The aims of this study are to describe difficult intravenous access (DIVA) and vascular access care provided to this patient population and to explore the differences between easy and DIVA groups.

Methods: A cohort study was conducted in patients with multimorbidity admitted to 2 hospitals between March and November 2013.

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Aim: To determine the impact of the Best Practice Spotlight Organization® initiative on nurses' perception of their work environment and their attitudes to evidence-based practice.

Design: Quasi-experimental, multicentre study. The intervention is the participation in Best Prectice Spotilight Organizations to implement Best Practice Guidelines.

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Background: The use of personal smartphones is a reality in healthcare settings. Current research is allowing us to understand in what ways they help with communication and decision making at the point of care and their impact on patient safety.

Objectives: The objectives of this study were to characterize the use of smartphones by nursing students, and assess their opinions about the use of such phones as a distracting factor during clinical practicum and smartphone restriction policies.

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The first chemical study of the marine sponge Callyspongia cf. californica widely distributed along the coasts of the Tropical Eastern Pacific led to the identification of a new family of amphiphilic derivatives called callyspongidic acids. The four isolated metabolites 1-4 feature a hydrophilic diacid end opposed to both an aromatic moiety and a long alkyl chain.

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Despite a large occurrence, especially over the Pacific Ocean, the chemical diversity of marine invertebrates belonging to the order Zoantharia is largely underexplored. For the two species of the genus no chemical study has been reported so far. The first chemical investigation of collected at the Marine Protected Area "El Pelado", Santa Elena, Ecuador, led to the isolation of four new ecdysteroid derivatives named ecdysonelactones.

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Aims And Objectives: To estimate the prevalence of difficult venous access in complex patients with multimorbidity and to identify associated risk factors.

Background: In highly complex patients, factors like ageing, the need for frequent use of irritant medication and multiple venous catheterisations to complete treatment could contribute to exhaustion of venous access.

Design: A cross-sectional study was conducted.

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