IL-6, TNF-α, IL-10, and nutritional status in pediatric patients with biliary atresia.

Objectives: The objective of the present study is to evaluate whether IL-6, TNF-α, IL-10 are associated with nutritional status in patients with cirrhosis secondary to biliary atresia and compare to healthy controls.

Methods: The parameters used for nutritional assessment were the standard deviation scores of height-for-age and of triceps skinfold thickness-for-age. The severity of cirrhosis was evaluated using the Child-Pugh score and PELD/MELD.

Serum proinflammatory cytokines and nutritional status in pediatric chronic liver disease.

Aim: To evaluate the nutritional status and its association with proinflammatory cytokines in children with chronic liver disease.

Methods: We performed a cross-sectional study with 43 children and adolescents, aged 0 to 17 years, diagnosed with chronic liver disease. All patients regularly attended the Pediatric Hepatology Unit and were under nutritional follow up.

Validation of a subjective global assessment questionnaire.

Objective: To validate the Subjective Global Nutritional Assessment (SGNA) questionnaire for Brazilian children and adolescents.

Methods: A cross-sectional study with 242 patients, aged 30 days to 13 years, treated in pediatric units of a tertiary hospital with acute illness and minimum hospitalization of 24h. After permission from the authors of the original study, the following criteria were observed to obtain the validation of SGNA instruments: translation and backtranslation, concurrent validity, predictive validity, and inter-observer reliability.