Impact of common polymorphisms in candidate genes for insulin resistance and obesity on weight loss of morbidly obese subjects after laparoscopic adjustable gastric banding and hypocaloric diet.

Context: It is unknown whether genetic factors that play an important role in body weight homeostasis influence the response to laparoscopic adjustable gastric banding (LAGB).

Objective: We investigated the impact of common polymorphisms in four candidate genes for insulin resistance on weight loss after LAGB.

Design: The design was a 6-month follow-up study.