Publications by authors named "Cristina Raluca Filimon"
Background: The sequential organ failure assessment (SOFA) score has poor discriminative ability for death in severely or critically ill patients with Coronavirus disease 2019 (COVID-19) requiring intensive care unit (ICU) admission. Our aim was to create a new score powered to predict 28-day mortality. Methods: Retrospective, observational, bicentric cohort study including 425 patients with COVID-19 pneumonia, acute respiratory failure and SOFA score ≥ 2 requiring ICU admission for ≥72 h.
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- - The study investigates how changes in specific blood ratios (NLR, PLR, MLR, SII, dNLR) during the first 48 hours of ICU admission can predict the need for invasive mechanical ventilation (IMV) and death in critical COVID-19 patients.
- - Analyzing data from 272 severe COVID-19 patients, the findings show that a change in NLR of more than 2 significantly predicts IMV needs, followed by changes in SII and dNLR.
- - For mortality prediction, an NLR greater than 11 was found to be the strongest indicator, alongside dNLR over 6.93 and SII above 3700.