Inhalation bioaccessibility of multi-class organic pollutants associated to atmospheric PM: Correlation with PM properties and health risk assessment.

Inhalation exposure to fine particulate matter (PM) represents a global concern due to the adverse effects in human health. In the last years, scientific community has been adopted the assessment of the PM-bound pollutant fraction that could be released (bioaccessible fraction) in simulated lung fluids (SLFs) to achieve a better understanding of PM risk assessment and toxicological studies. Thus, bioaccessibility of 49 organic pollutants, including 18 polycyclic aromatic hydrocarbons (PAHs), 12 phthalate esters (PAEs), 11 organophosphorus flame retardants (OPFRs), 6 synthetic musk compounds (SMCs) and 2 bisphenols in PM samples was evaluated.