[Proteinuria selectivity and prednisone response in children with nephrotic syndrome].

Background: The proteinuria selectivity index (PSI) can predict the response to prednisone in the primary nephrotic syndrome (PNS).

Objective: To determine the association of prednisone response with the PSI in patients with PNS.

Material And Methods: With analytical cross-sectional design, pediatric patients with PNS were studied with at least six months of prior follow-up, at the Nuevo Hospital Civil de Guadalajara from 2014 to 2015.

[Concordance of glomerular filtration rate with creatinine clearance in 24-hour urine and Schwartz and Schwartz updated].

Background: Reference methods for the quantification of the glomerular filtration rate (GFR) are difficult to use in clinical practice; formulas for evaluating GFR based on serum creatinine (SCr) and/or creatinine clearance are used. The aim of this study was to quantify the correlation and concordance of GFR with creatinine clearance in 24-hour urine (GFR24) and Schwartz and Schwartz updated formulas.

Methods: Cross-sectional study involving healthy pediatric patients and with chronic kidney disease (CKD) from 5 to 16.

[Upper and lower neural tube defects: prevalence and association with illnesses and drugs].

Objective: To determine the prevalence of upper and lower neural tube defects and identify its association with the exposure to illnesses and drugs during pregnancy.

Material And Methods: This is a case-control study of 107 newborns with upper neural tube defects, 59 with lower neural tube defects, and 166 newborns without malformations, in 56,926 consecutive births between 1989 and 1997. The exposure was documented by a direct interview to the mother of those subject of study.