Publications by authors named "Cristina Martinez-Pascual"
The authors wish to make the following corrections to this paper [...
View Article and Find Full Text PDF(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to investigate differences in the inflammatory profiles of macrophages derived from patients with cirrhosis due to either hepatitis C virus (HCV) or alcohol, focusing on their ascitic fluid.
- Patients with HCV-related cirrhosis showed distinct patterns of immune cell migration and cytokine levels in ascites, with a generally lower inflammatory response compared to alcohol-related cirrhosis.
- Findings indicated that HCV patients had higher IL-10 levels and lower levels of IL-6 and IL-12 in their ascitic fluid, while the primed status of peritoneal macrophages was maintained under laboratory conditions, with notable differences in cell signaling responses between the two patient groups.
Hepatoportal sclerosis (HPS) is characterized by presinusoidal intrahepatic portal hypertension associated with splenomegaly and anemia in patients with non-cirrhotic liver. Liver biopsy is essential, especially to rule out other processes. Being a disease of unknown etiology, the majority of cases have been described in eastern countries.
View Article and Find Full Text PDF