Publications by authors named "Cristina Martin Jimenez"

Article Synopsis
  • A retrospective study analyzed 100 veterinary vaccines evaluated by the European Medicines Agency (EMA) from 1996 to 2017 to understand the role of field efficacy studies in marketing authorization applications.
  • For 52 of these vaccines, field efficacy studies significantly influenced their efficacy claims and benefit-risk evaluations, while for another 24, their contributions were either minor or unclear.
  • The study also noted challenges in conducting field studies, as less than half of the applications that included such studies involved natural exposure, suggesting potential limitations in assessing vaccine effectiveness in real-world scenarios.
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Root-knot nematodes (genus Meloidogyne) are plant parasites causing huge economic loss in the agricultural industry and affecting severely numerous developing countries. Control methods against these plant pests are sparse, the preferred one being the deployment of plant cultivars bearing resistance genes against Meloidogyne species. However, M.

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Stomatal abundance varies widely across natural populations of , and presumably affects plant performance because it influences water and CO exchange with the atmosphere and thence photosynthesis and transpiration. In order to determine the genetic basis of this natural variation, we have analyzed a recombinant inbred line (RIL) population derived from the wild accession Ll-0 and the reference strain Landsberg (L), which show low and high stomatal abundance, respectively. Quantitative trait locus (QTL) analyses of stomatal index, stomatal density, and pavement cell density measured in the adaxial cotyledon epidermis, identified five loci.

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Root-knot nematodes (genus Meloidogyne) exhibit a diversity of reproductive modes ranging from obligatory sexual to fully asexual reproduction. Intriguingly, the most widespread and devastating species to global agriculture are those that reproduce asexually, without meiosis. To disentangle this surprising parasitic success despite the absence of sex and genetic exchanges, we have sequenced and assembled the genomes of three obligatory ameiotic and asexual Meloidogyne.

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Cell cycle control in galls provoked by root-knot nematodes involves the activity of inhibitor genes like the Arabidopsis ICK/KRP members. Ectopic KRP1, KRP2 and KRP4 expression resulted in decreased gall size by inhibiting mitotic activity, whereas KRP6 induces mitosis in galls. Herein, we investigate the role of KRP3, KRP5 and KRP7 during gall development and compared their role with previously studied members of this class of cell cycle inhibitors.

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