Publications by authors named "Cristina Interiano"

Background: SARS-CoV-2 infection in children does not seem to follow the same pattern as in adults. Limited information is published on the level of antibody production and the duration of antibody response in children with COVID-19. Moreover, it is unknown if all children have a similar immune response to the infection, or if there are age dependent differences.

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Background: Clinical laboratory testing has been an essential part of COVID-19 management. Serology can provide valuable information regarding a patient's exposure to virus, and may have a larger role to play as vaccines becomes available. Limited data is available on the serological response in pediatric patients.

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Article Synopsis
  • The study evaluates the reliability of five commercially available tests for measuring measles virus-specific IgG antibodies to determine immunity in individuals with uncertain vaccination status.
  • False-negative results can lead to unnecessary quarantine or revaccination, while false-positive results may allow susceptible individuals to inadvertently spread the disease.
  • Discrepancies were found mainly in low-positive samples, but overall, the tests performed well for confirming negative IgG status and intermediate to high levels of IgG, with about 11% of low-antibody sera yielding false negatives.
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