The first report of deep-sea litter in the South-Western Caribbean Sea.

Marine litter is a world-wide problem, but the knowledge on this topic in remote areas such as the poles and the deep-sea is still limited. This paper seeks to provide the first accounts of deep-sea litter in the South-Western Caribbean Sea. The survey used 5066 still images from ROV video surveys around four hydrocarbon exploratory drilling zones.

3D cultures of human neural progenitor cells: dopaminergic differentiation and genetic modification. [corrected].

Central nervous system (CNS) disorders remain a formidable challenge for the development of efficient therapies. Cell and gene therapy approaches are promising alternatives that can have a tremendous impact by treating the causes of the disease rather than the symptoms, providing specific targeting and prolonged duration of action. Hampering translation of gene-based therapeutic treatments of neurodegenerative diseases from experimental to clinical gene therapy is the lack of valid and reliable pre-clinical models that can contribute to evaluate feasibility and safety.