Publications by authors named "Cristina Gallego Lezaun"
Article Synopsis
- The study analyzed COVID-19 hospital admissions from 2020 in Spain, focusing on older patients during two pandemic waves, to evaluate mortality differences.
- Results showed a mortality rate of 20.4% during the first wave and 17.2% during the second wave, particularly among patients aged 70 and older, who had a significant mortality reduction of 7.6%.
- The lower mortality in the second wave may be due to improved healthcare standards, greater clinical experience, or less strain on the healthcare system, independent of patient or disease severity.
The significant impact of COVID-19 worldwide has made it necessary to develop tools to identify patients at high risk of severe disease and death. This work aims to validate the RIM Score-COVID in the SEMI-COVID-19 Registry. The RIM Score-COVID is a simple nomogram with high predictive capacity for in-hospital death due to COVID-19 designed using clinical and analytical parameters of patients diagnosed in the first wave of the pandemic.
View Article and Find Full Text PDFIntroduction And Objective: Transthyretin-associated familial amyloid polyneuropathy (TTR-FAP) is a disease caused by the deposit of abnormal transthyretin on tissues, mainly nerves. Small nerve fibers are altered earlier during the course of the disease; hence, detection of their involvement may have serious consequences on the natural history of disease.
Methods: A cross-sectional, observational study, was carried out on symptomatic patients, involving the conduct of several tests for small nerve fibers: Vibration, Touch Pressure (TP) and Heat Pain (HP).
The age of onset (AO) of hereditary ATTR amyloidosis (hATTR) is known to vary between populations, with differing characteristics reported according to AO in endemic/non-endemic foci. This was a retrospective study of patients with early AO (<50 years) and late AO (≥50 years) hATTR at our center in Mallorca. Data were collected on patient demographics, clinical disease manifestation, and physical symptoms.
View Article and Find Full Text PDFIgG4-related disease (IgG4-RD) is a recently described entity characterized by lymphoplasmacytic infiltrates, usually mimicking tumors, affecting almost every organ or system. Nevertheless, serosal involvement has been rarely reported. In this article, we report two cases of IgG4-RD with serosal involvement and review the literature.
View Article and Find Full Text PDFBackground: Interferon-γ release assays (IGRAs) are increasingly used for the diagnosis of latent tuberculosis infection (LTBI). Because of the lack of a gold standard for the diagnosis of LTBI, IGRAs are compared to the tuberculin skin test (TST) and yield conflicting results. We assessed the usefulness of an IGRA test, QuantiFERON(®)-TB Gold In-Tube (QFT-G-IT), for diagnosing LTBI compared with TST in the setting of a contact screening study.
View Article and Find Full Text PDFArticle Synopsis
- Transthyretin-associated Familial Amyloid Polyneuropathy (TTR-FAP) is a genetic disorder caused by a mutation leading to the abnormal protein transthyretin, with a notable incidence in Majorca, Spain.
- A retrospective study of 75 patients at Son Llàtzer Hospital revealed that nearly half were asymptomatic, with a mean age of 58.3 years and many having undergone liver transplants due to the disease.
- The majority of patients presented with nervous system impairments, and a significant family history was noted, indicating the condition's hereditary nature and the relevance of early diagnosis and management strategies.
Introduction: Q fever is a widespread zoonotic infection caused by Coxiella burnetii (C. burnetii). Acute infection varies from a self-limited flu-like illness to pneumonia or hepatitis.
View Article and Find Full Text PDF