Publications by authors named "Cristina Brunel"

Article Synopsis
  • This study examines the brain activity of patients with borderline personality disorder (BPD) while performing a working memory task using fMRI scanning.
  • The results indicate that BPD patients showed reduced activation in certain brain areas during task performance compared to healthy controls and displayed a failure to deactivate specific brain regions.
  • These findings suggest a slight hypoactivation in the frontal areas of BPD patients during cognitive tasks, which is not solely linked to previous depression history.
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Background: Structural imaging studies of borderline personality disorder (BPD) have found regions of reduced cortical volume, but these have varied considerably across studies. Reduced hippocampus and amygdala volume have also been a regular finding in studies using conventional volumetric measurement. How far comorbid major depression, which is common in BPD and can also affect in brain structure, influences the findings is not clear.

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