The Mediterranean Sea represents a natural laboratory to infer the possible impacts of climate change and ocean acidification. In this article, we report the deteriorating ability of sea urchin larvae (Paracentrotus lividus) to cope with toxicity of a reference contaminant (Cu EC) over the past 20 years and assessed the influence of 5 environmental factors from satellite measurements. This timeframe was divided in before and after January 2016 (46.
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