Efficient Silver Release From Ion Exchange Silver Dressings in Biologically Relevant Media.

Introduction: Silver-containing wound dressings commonly are used when there is a risk of infection. These commercial antimicrobial silver dressings have various compositions that use different substrates and/or silver sources. Common silver sources are ionic silver (Ag+) and metallic silver (Ag0).

MRI compatibility of silver based wound dressings.

As silver dressings gain more widespread use, it is more likely that patients with silver-based dressings will also undergo magnetic resonance imaging (MRI). In current practice, these dressings are removed prior to imaging due to concerns over heating and image distortion. As dressing changes can be painful, the need to remove dressings simply for MRI may increase pain and contribute to opioid dependency.

Spasmolytic activity of Artemisia copa aqueous extract and isolated compounds.

Artemisia copa Phil. (Compositae) is used in popular medicine as a digestive and for gastric pains. The effects of A.

Vicenin-2, a potential anti-inflammatory constituent of Urtica circularis.

Vicenin-2 (1), a flavonoid glycoside, was isolated and identified from an ethanol extract of the aerial parts of Urtica circularis. This crude extract was found to possess significant anti-inflammatory activity in a carrageenan-induced rat hind paw edema model (41.5% inhibition at a dose of 300 mg/kg; ip).

Psychopharmacological effects of Artemisia copa aqueous extract in mice.

Objective: To evaluate the aqueous extract from aerial parts of Artemisia copa Phil. (Asteraceae) administered orallyfor its psychopharmacological activities in several experimental models.

Methods: The extract was administered p.

Evaluation of antinociceptive, antinflammatory activities and phytochemical analysis of aerial parts of Urtica urens L.

The antinociceptive and antiinflammatory activities of the ethanol extract of the aerial part of Urtica urens were determined by experimental animal models. U. urens extract was found to possess significant antinociceptive activity in chemically induced mouse pain models (ED₅₀ 39.

Synthesis and Spectroscopic Correlation of the Diastereoisomers of 2,3-Dihydroxy-2,6,8-trimethyldeca-(4, 6)-dienoic Acid: Implications for the Structures of Papuamides A-D and Mirabamides A-D.

All 4 diastereomeric possibilities for the 2,3-dihydroxy-2,6,8-trimethyldeca-(4,6)-dienoic acid (Dhtda) residue, found in the cyclic depsipeptide natural products papuamides A-D and mirabamides A-D, were stereoselectively synthesized using a -selective Wittig reaction of both enantiomers of 2,4-dimethylhex-2-enyl-triphenylphosphonium bromide with all four diastereoisomers of ethyl-3-formyl-2-methyl-1,4-dioxaspiro[4,4]nonane-2-carboxylate. To elucidate the configuration of Dhtda, the H- and C-NMR spectra of the synthetic isomers were compared to those of the natural residue. On the basis of that comparison, it is suggested that the likely configuration of the diastereomer present in Dhtda residue is either (2,3,8) or (2,3,8) in the papuamides and mirabimides.

Biological dosimetry and Bayesian analysis of chromosomal damage in thyroid cancer patients.

Chromosomal damage was investigated in lymphocytes of thyroid cancer patients after radioiodine treatment. An assay on micronuclei (MN) in binucleated cells was performed in blood samples of 25 patients 3 d after (131)I (3.7 GBq) was given.

Neuropharmacological activity of Eupatorium buniifolium aqueous extract in mice.

The aim of this study was to evaluate the neuropharmacological profile of the Eupatorium buniifolium aqueous extract (EB) in mice. EB at doses up to 1.5 g/kg p.

Flavonoids from Artemisia copa with anti-inflammatory activity.

Bioactivity-guided fractionation of the dichloromethane and ethanol extracts from the aerial parts of Artemisia copa led to the isolation of the flavonoids spinacetin, jaceosidin, axillarin, penduletin, tricin and chrysoeriol. These compounds were studied for possible inhibitory activity on the generation of inflammatory mediators in a cell line of mouse macrophages (RAW 264.7) stimulated with lipopolysaccharide.

Metabolites from endophytes of the medicinal plant Erythrina crista-galli.

Erythrina crista-galli (Fabaceae) is used in Argentinean ethnopharmacology as anti-inflammatory medication, narcotic, desinfectant, and for the treatment of wounds. The common name of the tree is "ceibo" or coral tree. The dominating endophytes in E.