A novel therapeutic phosphate-based glass improves full-thickness wound healing in a rat model.

Wound healing is a highly dynamic process and innovative therapeutic approaches are currently developed to address challenges of providing optimal wound care. In this study, phosphate-based glasses in the (CuO) ·(KPO ) ·(ZnO) ·(Ag O) system (CuKPO ZnAg), with different CuO/ KPO ratios were prepared by melt-quenching technique. Constant Cu concentrations were released from the samples during immersion in Simulated Body Fluid (SBF), while Zn concentrations were slightly decreased over time.