Inspiratory resistive loading after all-out exercise improves subsequent performance.

We have previously shown that post-exercise inspiratory resistive loading (IRL) reduces blood lactate ([Lac(b)(-)]). In this study, we tested the hypothesis that IRL during recovery could improve subsequent exercise performance. Eight healthy men underwent, on different days, two sequential 30-s, cycle ergometer Wingate tests.

Inspiratory muscle training improves blood flow to resting and exercising limbs in patients with chronic heart failure.

Objectives: We tested the hypothesis that inspiratory muscle loading could result in exaggerated peripheral vasoconstriction in resting and exercising limbs and that inspiratory muscle training (IMT) could attenuate this effect in patients with chronic heart failure (CHF) and inspiratory muscle weakness.

Background: Inspiratory muscle training improves functional capacity of patients with CHF, but the mechanisms of this effect are unknown.

Methods: Eighteen patients with CHF and inspiratory muscle weakness (maximal inspiratory pressure <70% of predicted) and 10 healthy volunteers participated in the study.

Attenuation of muscle metaboreflex in chronic obstructive pulmonary disease.

Purpose: Abnormal skeletal muscle function is well documented in chronic obstructive pulmonary disease, but there is no information about the activity of muscle metabosensitive afferents. In this study, we tested the hypothesis that patients with chronic obstructive pulmonary disease would have abnormal reflex responses to stimulation of metabosensitive afferents in skeletal muscle when compared with healthy, matched subjects.

Methods: In 16 patients with moderate to severe chronic obstructive pulmonary disease and 13 healthy, age-matched control subjects, we evaluated heart rate, mean blood pressure, calf blood flow, and calf vascular resistance responses to static handgrip exercise at 30% of maximal voluntary contraction, followed by recovery with or without circulatory occlusion.

Blood lactate during recovery from intense exercise: impact of inspiratory loading.

Purpose: It has long been suggested that inspiratory muscle activity may impact blood lactate levels ([Lac(-)]B) during the recovery from dynamic exercise. In this study, we tested the hypothesis that inspiratory muscle activation during recovery from intense exercise would contribute to La clearance, thus leading to reduced [Lac(-)]B.

Methods: Twelve healthy men underwent two maximal, incremental exercise tests on different days.

Muscle metaboreflex contribution to resting limb haemodynamic control is preserved in older subjects.

Ageing is associated with tonic elevations in basal sympathetic vasoconstrictor outflow to skeletal muscle and a parallel decline in vascular function. The purpose of this study was to test the hypothesis that older individuals exhibit attenuated calf vascular resistance (CVR) responses to muscle metaboreflex activation in comparison with young subjects. Fourteen young (mean +/- SD age 23 +/- 3 years) and 13 older (62 +/- 7 years) sedentary subjects participated in the study.