Publications by authors named "Cristiane Candida do Amaral"
Background: Paracoccidioidomycosis (PCM) is a systemic mycosis commonly found in Latin America that is caused by distinct species of Paracoccidioides genus: Paracoccidioides brasiliensis complex (S1, PS2, PS3 and PS4) and Paracoccidioides lutzii. Its pathobiology has been recently explored by different approaches to clarify the mechanisms of host-pathogen interactions underpinning PCM. The diversity of clinical forms of this disease has been attributed to both host- and fungus-related factors.
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- The study examined the potential natural infection of dogs by the fungus Paracoccidioides brasiliensis in Brazil, surveying 149 urban and 126 rural dogs using specific tests.
- Out of the urban dogs, 6.2% showed positive intradermal tests, but no significant fungal presence was found in histopathological examinations or cultures.
- In contrast, a high percentage (80.5%) of rural dogs tested positive for antibodies against the fungus, suggesting they are more commonly infected while indicating a natural resistance to developing the disease.
The profiles of proteins present in the exoantigens of Brazilian Sporothrix schenckii isolates were studied and compared by electrophoresis (SDS-PAGE). Thirteen isolates from five different regions of Brazil (1,000 to 2,000 km apart) and ten from a more limited region (200 to 400 km apart within the state of São Paulo) were cultured in Sabouraud, M199 and minimum (MM) media. Qualitative and quantitative differences in the expression of proteins, which varied according to the medium and the isolate, were observed.
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