Retinal Nerve Fiber Layer Optical Texture Analysis and 10-2 Visual Field Assessment in Glaucoma.

Purpose: To apply retinal nerve fiber layer (RNFL) optical texture analysis (ROTA) to 1) investigate the association between papillomacular and papillofoveal bundle defects with 10-2 visual field (VF) sensitivity abnormalities, and 2) integrate the information from RNFL bundle defect and 24-2 VF central test locations to determine the likelihood of 10-2 VF sensitivity abnormalities.

Design: Cross-sectional.

Methods: A total of 841 eyes (144 healthy, 317 glaucoma suspect, and 380 glaucoma) of 442 participants were included.

Comparison of the TEMPO binocular perimeter and Humphrey field analyzer.

This study compared between TEMPO, a new binocular perimeter, with the Humphrey Field Analyzer (HFA). Patients were tested with both TEMPO 24-2 Ambient Interactive Zippy Estimated by Sequential Testing (AIZE)-Rapid and HFA 24-2 Swedish Interactive Threshold Algorithm (SITA)-Fast in a randomized sequence on the same day. Using a mixed-effects model, visual field (VF) parameters and reliability indices were compared.

Comparison of the TEMPO Binocular Perimeter and Humphrey Field Analyzer.

This study compared between TEMPO, a new binocular perimeter, with the Humphrey Field Analyzer (HFA). Patients were tested with both TEMPO 24 - 2 AIZE-Rapid and HFA 24 - 2 SITA-Fast in a randomized sequence on the same day. Using a mixed-effects model, visual field (VF) parameters and reliability indices were compared.

Long-term intraocular pressure fluctuations and risk of conversion from ocular hypertension to glaucoma.

Purpose: To investigate whether long-term intraocular pressure (IOP) fluctuations are a risk factor for conversion from ocular hypertension to glaucoma.

Design: Observational cohort study.

Participants: The study included 252 eyes of 126 patients with ocular hypertension observed untreated as part of the Diagnostic Innovations in Glaucoma Study.

Agreement between stereophotographic and confocal scanning laser ophthalmoscopy measurements of cup/disc ratio: effect on a predictive model for glaucoma development.

Objective: To evaluate risk estimates obtained by incorporating confocal scanning laser ophthalmoscopy measurements of cup/disc (C/D) ratio into a previously described and validated predictive model to estimate the risk of glaucoma development in ocular hypertension. These risk estimates were compared with those obtained by the original model in which vertical C/D ratio was estimated from stereophotographs.

Design: Cross-sectional study.

Long-term variability of GDx VCC retinal nerve fiber layer thickness measurements.

Purpose: To evaluate the long-term variability of GDx VCC retinal nerve fiber layer (RNFL) thickness measurements.

Methods: The study enrolled a cohort of glaucoma suspects who did not develop any evidence of visual field damage or change in the appearance of the optic nerve during an average follow-up of 9.1+/-3.

Structure and function evaluation (SAFE): II. Comparison of optic disk and visual field characteristics.

Purpose: To evaluate the relationship between glaucomatous structural damage to the optic nerve and development of visual field loss with standard automated perimetry (SAP) and short wavelength automated perimetry (SWAP).

Design: Cohort study.

Methods: Patients with elevated intraocular pressure and normal SAP visual fields were enrolled in this prospective study.

Imaging of the optic disc and retinal nerve fiber layer: the effects of age, optic disc area, refractive error, and gender.

We cross-sectionally examined the relationship between age, optic disc area, refraction, and gender and optic disc topography and retinal nerve fiber layer (RNFL) measurements, using optical imaging techniques. One eye from each of 155 Caucasian subjects (age range 23.0-80.