Publications by authors named "Cristiana Pedone"
Background: The impact of radiotherapy (RT) in neuroendocrine neoplasms is still unknown, and outcomes could be improved by a better insight in RT response predictors. This retrospective analysis investigates the potential correlation between Ki-67 and RT response to evaluate its role as biological marker of radiosensitivity.
Material And Methods: Data from patients treated at an Italian NET-referral center between 2015 and 2020 were retrieved.
Article Synopsis
- Neoadjuvant short-course radiotherapy (SCRT) for locally advanced rectal cancer (LARC) is typically delivered using photons, but proton beam therapy (PBT) may reduce acute side effects and improve chemotherapy tolerance.
- A study comparing SCRT with photons and protons showed that PBT significantly lowers radiation exposure to pelvic organs like the bladder and bowel while maintaining similar treatment quality.
- The findings suggest that PBT could offer clinical benefits for LARC patients, with further implications to be detailed in future reports from the ongoing PRORECT trial.