Publications by authors named "Cristian Melgarejo"
Mycobacterium microti is a member of the Mycobacterium tuberculosis complex that seldom causes disease in livestock and humans. This study evaluated the effects on immunodiagnosis and the pathological findings in goats after experimental exposure by different routes and doses to M. microti.
View Article and Find Full Text PDFRotavirus A (RVA) is a common cause of diarrhea in newborn pigs, leading to significant economic losses. RVA is considered a major public health concern due to genetic evolution, high prevalence, and pathogenicity in humans and animals. The objective of this study was to identify and characterize RVA in swine farms in Chile.
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- Goats are being studied as a model for tuberculosis (TB) to evaluate new vaccines and treatments, comparing two methods of infection: intranasal (IN) and endobronchial (EB).
- Fourteen goats were divided into two groups and monitored for clinical signs and immune responses over nine weeks, after which they were euthanized for detailed examinations of lung lesions and bacterial loads.
- Results showed that the IN method resulted in slower disease progression and less severe lung damage compared to the EB method, indicating that the route of infection significantly affects the study of TB and vaccine testing.
This study aimed to assess the efficacy of a heat-inactivated Mycobacterium caprae (HIMC) vaccine in goats experimentally challenged with the same strain of M. caprae. Twenty-one goats were divided into three groups of seven: vaccinated with heat-inactivated Mycobacterium bovis (HIMB), with HIMC and unvaccinated.
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